[HTML][HTML] The role of extracellular Vesicles in the pathogenesis and treatment of rheumatoid arthritis and osteoarthritis

E Bakinowska, K Kiełbowski, A Pawlik - Cells, 2023 - mdpi.com
Cells can communicate with each other through extracellular vesicles (EVs), which are
membrane-bound structures that transport proteins, lipids and nucleic acids. These …

[HTML][HTML] Role of extracellular vesicles in rheumatoid arthritis

H Fu, D Hu, L Zhang, P Tang - Molecular immunology, 2018 - Elsevier
Cell-derived extracellular vesicles (EVs) are involved in the pathogenesis of rheumatoid
arthritis (RA), playing important roles in antigen presentation, inflammation, angiogenesis …

Update on the role of extracellular vesicles in rheumatoid arthritis

H Miao, F Wang, S Lin, Z Chen - Expert Reviews in Molecular …, 2022 - cambridge.org
Rheumatoid arthritis (RA) is a heterogeneous autoimmune disorder that leads to severe joint
deformities, negatively affecting the patient's quality of life. Extracellular vesicles (EVs) …

[HTML][HTML] Pathogenic or therapeutic extracellular vesicles in rheumatic diseases: role of mesenchymal stem cell-derived vesicles

S Cosenza, M Ruiz, M Maumus, C Jorgensen… - International journal of …, 2017 - mdpi.com
Extracellular vesicles (EVs) are important mediators of cell-to-cell communication pathways
via the transport of proteins, mRNA, miRNA and lipids. There are three main types of EVs …

The developing role of extracellular vesicles in autoimmune diseases: special attention to mesenchymal stem cell-derived extracellular vesicles

GGR Ortiz, NH Zaidi, RS Saini, AAR Coronel… - International …, 2023 - Elsevier
Autoimmune diseases are complex, chronic inflammatory conditions initiated by the loss of
immunological tolerance to self-antigens. Nowadays, there is no effective and useful therapy …

Extracellular vesicles as novel approaches for the treatment of osteoarthritis: a narrative review on potential mechanisms

SS Jousheghan, MM Sajjadi, SS Jousheghan… - Journal of Molecular …, 2021 - Springer
Osteoarthritis (OA) is a progressive degeneration of articular cartilage with involvement of
synovial membrane, and subchondral bone. Current treatment approaches have focused on …

[HTML][HTML] Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis

Z Liu, Y Zhuang, L Fang, C Yuan, X Wang, K Lin - Bioactive Materials, 2023 - Elsevier
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …

Extracellular vesicles as drug delivery vehicles for rheumatoid arthritis

IK Kim, SH Kim, SM Choi, BS Youn… - Current Stem Cell …, 2016 - ingentaconnect.com
Rheumatoid arthritis (RA) is a chronic, systemic and progressive autoimmune disease of
connective tissues common in middle age. Dysregulation of the tissue homeostasis …

[HTML][HTML] Extracellular vesicles in rheumatoid arthritis and systemic lupus erythematosus: functions and applications

B Zhang, M Zhao, Q Lu - Frontiers in immunology, 2021 - frontiersin.org
In the last two decades, extracellular vesicles (EVs) have aroused wide interest among
researchers in basic and clinical research. EVs, small membrane vesicles are released by …

[HTML][HTML] Extracellular vesicles from mesenchymal stem cells as potential treatments for osteoarthritis

NA Mohd Noor, A Abdullah Nurul… - Cells, 2021 - mdpi.com
Osteoarthritis (OA) is a chronic degenerative disorder of the joint and its prevalence and
severity is increasing owing to ageing of the population. Osteoarthritis is characterized by …