Coilin is a nuclear phosphoprotein that concentrates within Cajal bodies (CBs) and impacts
small nuclear ribonucleoprotein (snRNP) biogenesis. Cisplatin and γ-irradiation, which …

Coilin is widely known as the protein marker of the Cajal body, a subnuclear domain
important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complexes …

The Cajal body (CB) is a domain of concentrated components found within the nucleus of
cells in an array of species that is functionally important for the biogenesis of telomerase and …

Coilin is a nuclear phosphoprotein that accumulates in Cajal bodies (CBs). CBs participate
in ribonucleoprotein and telomerase biogenesis, and are often found in cells with high …

Cajal bodies are important nuclear structures containing proteins that preferentially regulate
RNA-related metabolism. We investigated the cell-type specific nuclear distribution of Cajal …

Cajal bodies (CBs) are nuclear structures that are thought to have diverse functions,
including small nuclear ribonucleoprotein (snRNP) biogenesis. The phosphorylation status …

Coilin is a conserved protein essential for integrity of nuclear membrane-less inclusions
called Cajal bodies. Here, we report an amino acid substitution (p. K496E) found in a widely …

Initially identified as a marker of coiled bodies (now Cajal bodies or CBs), the protein coilin
was discovered a quarter of century ago. Coilin is now known to scaffold the CB, but its …

Coilin is a nuclear protein that plays a role in Cajal body formation. The function of
nucleoplasmic coilin is unknown. Here we report that coilin interacts with Ku70 and Ku80 …

Coilin protein scaffolds Cajal bodies (CBs)—subnuclear compartments enriched in small
nuclear RNAs (snRNAs)—and promotes efficient spliceosomal snRNP assembly. The …