Coilin participates in the suppression of RNA polymerase I in response to cisplatin-induced DNA damage
AS Gilder, PM Do, ZI Carrero, AM Cosman… - Molecular biology of …, 2011 - Am Soc Cell Biol
Coilin is a nuclear phosphoprotein that concentrates within Cajal bodies (CBs) and impacts
small nuclear ribonucleoprotein (snRNP) biogenesis. Cisplatin and γ-irradiation, which …
small nuclear ribonucleoprotein (snRNP) biogenesis. Cisplatin and γ-irradiation, which …
Coilin displays differential affinity for specific RNAs in vivo and is linked to telomerase RNA biogenesis
HJ Broome, MD Hebert - Journal of molecular biology, 2013 - Elsevier
Coilin is widely known as the protein marker of the Cajal body, a subnuclear domain
important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complexes …
important to the biogenesis of small nuclear ribonucleoproteins and telomerase, complexes …
Phosphorylation regulates coilin activity and RNA association
HJ Broome, ZI Carrero, HE Douglas… - Biology …, 2013 - journals.biologists.com
The Cajal body (CB) is a domain of concentrated components found within the nucleus of
cells in an array of species that is functionally important for the biogenesis of telomerase and …
cells in an array of species that is functionally important for the biogenesis of telomerase and …
Coilin phosphomutants disrupt Cajal body formation, reduce cell proliferation and produce a distinct coilin degradation product
ZI Carrero, V Velma, HE Douglas, MD Hebert - PLoS One, 2011 - journals.plos.org
Coilin is a nuclear phosphoprotein that accumulates in Cajal bodies (CBs). CBs participate
in ribonucleoprotein and telomerase biogenesis, and are often found in cells with high …
in ribonucleoprotein and telomerase biogenesis, and are often found in cells with high …
Coilin is rapidly recruited to UVA-induced DNA lesions and γ-radiation affects localized movement of Cajal bodies
E Bártová, V Foltánková, S Legartová, P Sehnalová… - Nucleus, 2014 - Taylor & Francis
Cajal bodies are important nuclear structures containing proteins that preferentially regulate
RNA-related metabolism. We investigated the cell-type specific nuclear distribution of Cajal …
RNA-related metabolism. We investigated the cell-type specific nuclear distribution of Cajal …
Cajal-body formation correlates with differential coilin phosphorylation in primary and transformed cell lines
SM Hearst, AS Gilder, SS Negi, MD Davis… - Journal of cell …, 2009 - journals.biologists.com
Cajal bodies (CBs) are nuclear structures that are thought to have diverse functions,
including small nuclear ribonucleoprotein (snRNP) biogenesis. The phosphorylation status …
including small nuclear ribonucleoprotein (snRNP) biogenesis. The phosphorylation status …
A point mutation in human coilin prevents Cajal body formation
DA Basello, AG Matera, D Staněk - Journal of Cell Science, 2022 - journals.biologists.com
Coilin is a conserved protein essential for integrity of nuclear membrane-less inclusions
called Cajal bodies. Here, we report an amino acid substitution (p. K496E) found in a widely …
called Cajal bodies. Here, we report an amino acid substitution (p. K496E) found in a widely …
Coilin: The first 25 years
M Machyna, KM Neugebauer, D Staněk - RNA biology, 2015 - Taylor & Francis
Initially identified as a marker of coiled bodies (now Cajal bodies or CBs), the protein coilin
was discovered a quarter of century ago. Coilin is now known to scaffold the CB, but its …
was discovered a quarter of century ago. Coilin is now known to scaffold the CB, but its …
[HTML][HTML] Coilin interacts with Ku proteins and inhibits in vitro non-homologous DNA end joining
V Velma, ZI Carrero, AM Cosman, MD Hebert - FEBS letters, 2010 - Elsevier
Coilin is a nuclear protein that plays a role in Cajal body formation. The function of
nucleoplasmic coilin is unknown. Here we report that coilin interacts with Ku70 and Ku80 …
nucleoplasmic coilin is unknown. Here we report that coilin interacts with Ku70 and Ku80 …
The coilin interactome identifies hundreds of small noncoding RNAs that traffic through Cajal bodies
M Machyna, S Kehr, K Straube, D Kappei, F Buchholz… - Molecular cell, 2014 - cell.com
Coilin protein scaffolds Cajal bodies (CBs)—subnuclear compartments enriched in small
nuclear RNAs (snRNAs)—and promotes efficient spliceosomal snRNP assembly. The …
nuclear RNAs (snRNAs)—and promotes efficient spliceosomal snRNP assembly. The …