Metformin: an old drug with new applications
Metformin is a biguanide drug that has been used to treat type 2 diabetes mellitus for more
than 60 years. The United Kingdom Prospective Diabetic Study (UKPDS) has shown …
than 60 years. The United Kingdom Prospective Diabetic Study (UKPDS) has shown …
Metformin in therapeutic applications in human diseases: Its mechanism of action and clinical study
Y Du, YJ Zhu, YX Zhou, J Ding, JY Liu - Molecular Biomedicine, 2022 - Springer
Metformin, a biguanide drug, is the most commonly used first-line medication for type 2
diabetes mellites due to its outstanding glucose-lowering ability. After oral administration of …
diabetes mellites due to its outstanding glucose-lowering ability. After oral administration of …
Metformin and its benefits for various diseases
Z Lv, Y Guo - Frontiers in endocrinology, 2020 - frontiersin.org
Metformin is a widely used biguanide drug due to its safety and low cost. It has been used
for over 60 years to treat type 2 diabetes at the early stages because of its outstanding ability …
for over 60 years to treat type 2 diabetes at the early stages because of its outstanding ability …
[HTML][HTML] Systematic review: Preventive and therapeutic applications of metformin in liver disease
A Bhat, G Sebastiani, M Bhat - World journal of hepatology, 2015 - ncbi.nlm.nih.gov
Metformin, a biguanide derivative, is the most commonly prescribed medication in the
treatment of type 2 diabetes mellitus. More recently, the use of metformin has shown …
treatment of type 2 diabetes mellitus. More recently, the use of metformin has shown …
Metformin: A review of potential mechanism and therapeutic utility beyond diabetes
S Dutta, RB Shah, S Singhal, SB Dutta… - Drug Design …, 2023 - Taylor & Francis
Metformin has been designated as one of the most crucial first-line therapeutic agents in the
management of type 2 diabetes mellitus. Primarily being an antihyperglycemic agent …
management of type 2 diabetes mellitus. Primarily being an antihyperglycemic agent …
Metformin: the hidden chronicles of a magic drug
Metformin, a biguanide is well known treatment for type 2 diabetes mellitus that has diverse
mechanism of actions. Various studies have elucidated the role of this drug in different …
mechanism of actions. Various studies have elucidated the role of this drug in different …
Metformin and metabolic diseases: a focus on hepatic aspects
Metformin has been widely used as a first-line anti-diabetic medicine for the treatment of
type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses …
type 2 diabetes (T2D). As a drug that primarily targets the liver, metformin suppresses …
Multifaceted mechanisms of action of metformin which have been unraveled one after another in the long history
H Kaneto, T Kimura, A Obata, M Shimoda… - International Journal of …, 2021 - mdpi.com
While there are various kinds of drugs for type 2 diabetes mellitus at present, in this review
article, we focus on metformin which is an insulin sensitizer and is often used as a first …
article, we focus on metformin which is an insulin sensitizer and is often used as a first …
[HTML][HTML] Metformin: Is it a drug for all reasons and diseases?
CR Triggle, I Mohammed, K Bshesh, I Marei, K Ye… - Metabolism, 2022 - Elsevier
Metformin was first used to treat type 2 diabetes in the late 1950s and in 2022 remains the
first-choice drug used daily by approximately 150 million people. An accumulation of …
first-choice drug used daily by approximately 150 million people. An accumulation of …
The current and potential therapeutic use of metformin—the good old drug
J Drzewoski, M Hanefeld - Pharmaceuticals, 2021 - mdpi.com
Metformin, one of the oldest oral antidiabetic agents and still recommended by almost all
current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become …
current guidelines as the first-line treatment for type 2 diabetes mellitus (T2DM), has become …