Autophagy in diabetic kidney disease: regulation, pathological role and therapeutic potential

D Yang, MJ Livingston, Z Liu, G Dong, M Zhang… - Cellular and Molecular …, 2018 - Springer
Diabetic kidney disease, a leading cause of end-stage renal disease, has become a serious
public health problem worldwide and lacks effective therapies. Autophagy is a highly …

[HTML][HTML] Autophagy and its therapeutic potential in diabetic nephropathy

YP Han, LJ Liu, JL Yan, MY Chen, XF Meng… - Frontiers in …, 2023 - frontiersin.org
Diabetic nephropathy (DN), the leading cause of end-stage renal disease, is the most
significant microvascular complication of diabetes and poses a severe public health concern …

Autophagy as a therapeutic target in diabetic nephropathy

Y Tanaka, S Kume, M Kitada… - Journal of Diabetes …, 2012 - Wiley Online Library
Diabetic nephropathy is a serious complication of diabetes mellitus, and its prevalence has
been increasing worldwide. Therefore, there is an urgent need to identify a new therapeutic …

[HTML][HTML] Autophagy in diabetic nephropathy

Y Ding, ME Choi - The Journal of endocrinology, 2015 - ncbi.nlm.nih.gov
Diabetic nephropathy (DN) is the most common cause of end-stage kidney disease
worldwide, and is associated with increased morbidity and mortality in patients with both …

The role of autophagy in the pathogenesis of diabetic nephropathy

K Yamahara, M Yasuda, S Kume… - Journal of diabetes …, 2013 - Wiley Online Library
Diabetic nephropathy is a leading cause of end‐stage renal disease worldwide. The
multipronged drug approach targeting blood pressure and serum levels of glucose, insulin …

Regulating autophagy as a therapeutic target for diabetic nephropathy

M Kitada, Y Ogura, I Monno, D Koya - Current diabetes reports, 2017 - Springer
Abstract Purpose of Review Autophagy promotes cellular health in response to various
cellular stresses and to changes in nutrient conditions. In this review, we focus on the role of …

[HTML][HTML] Autophagy dysregulation in diabetic kidney disease: from pathophysiology to pharmacological interventions

CD Gonzalez, MP Carro Negueruela… - Cells, 2021 - mdpi.com
Diabetic kidney disease (DKD) is a frequent, potentially devastating complication of diabetes
mellitus. Several factors are involved in its pathophysiology. At a cellular level, diabetic …

[HTML][HTML] Autophagy: a novel therapeutic target for diabetic nephropathy

S Kume, D Koya - Diabetes & metabolism journal, 2015 - synapse.koreamed.org
Diabetic nephropathy is a leading cause of end stage renal disease and its occurance is
increasing worldwide. The most effective treatment strategy for the condition is intensive …

Emerging role of autophagy in kidney function, diseases and aging

TB Huber, CL Edelstein, B Hartleben, K Inoki, M Jiang… - Autophagy, 2012 - Taylor & Francis
Autophagy is a highly conserved process that degrades cellular long-lived proteins and
organelles. Accumulating evidence indicates that autophagy plays a critical role in kidney …

Autophagy in kidney health and disease

Z Wang, ME Choi - Antioxidants & redox signaling, 2014 - liebertpub.com
Significance: Autophagy is emerging as an important pathway in many biological processes
and diseases. This review summarizes the current progress on the role of autophagy in …