Current treatments for alcohol use disorder (AUD) show large heterogeneity in response
and thus limited effectiveness and high relapse rates. A precision medicine approach with …

Defining the drug-induced neuroadaptations specifically associated with the behavioral
manifestation of addiction is a daunting task. To address this issue, we used a behavioral …

Alcohol use disorder (AUD) is a severe chronic condition characterized by compulsive
alcohol use, cravings and high relapse rates even after long periods of abstinence. It is …

This pilot study investigated psilocybin-induced changes in neural reactivity to alcohol and
emotional cues in patients with alcohol use disorder (AUD). Participants were recruited from …

Developing novel treatments for alcohol use disorders (AUDs) is of paramount importance
for improving patient outcomes and alleviating the suffering related to the disease. A better …

Background Alcohol Use Disorder (AUD) kills over 3 million people annually, accounting for
5.1% of global disease burden. The inefficacy of standard treatments has been linked to the …

Alcohol use disorder (AUD) remains a major global public health concern. In the US,
patterns of excessive drinking over short periods, termed binge drinking, are becoming …

Alcohol use disorders (AUDs) are a major health and social problem worldwide. Brain
stimulation holds great promise as an investigational tool to help us understand the …

Long-term binge alcohol consumption alters the signaling of numerous neurotransmitters in
the brain including noradrenaline (NE) and serotonin (5-HT). Alterations in the signaling of …

Substance use disorders (SUDs) are characterized by maladaptive signaling in the
prefrontal cortex and associated regions, however precisely how these drug-induced …