The endothelium, a tissue that forms a single layer of cells lining various organs and cavities
of the body, especially the heart and blood as well as lymphatic vessels, plays a complex …

Traditionally, non-cancer diseases are not considered as health risks following exposure to
low doses of ionizing radiation. Indeed, non-cancer diseases are classified as deterministic …

Radiation-induced endothelial/vascular injury is a major complicating factor in radiotherapy
and a leading cause of morbidity and mortality in nuclear or radiological catastrophes …

Exposure to ionizing radiation induces not only apoptosis but also senescence. While the
role of endothelial cell apoptosis in mediating radiation-induced acute tissue injury has been …

In radiation therapy for cancer, the therapeutic ratio represents an optimal balance between
tumor control and normal tissue complications. As improvements in the therapeutic arsenal …

The evaluation of the health effects of low-dose ionizing radiation has always been a focus
of debate and investigation within the scientific community. During the last decade …

The association between late damage in irradiated tissues and the vasculature was reported
shortly after the discovery of X-rays. Gross blood vessel abnormalities were a consistent …

Irradiation exposure is known to induce an inflammatory reaction. Endothelial cells play a
crucial role both in the inflammatory process and in radiation damage. Therefore …

Gamma radiation impairs vascular function, leading to the depression of endothelium‐
dependent vasodilatation. Loss of the nitric oxide (NO) pathway has been implicated, but …

Epidemiological studies have shown a clear association between therapeutic doses of
thoracic irradiation and increased risk of cardiovascular disease in long-term cancer …