Histiocytosis

JF Emile, F Cohen-Aubart, M Collin, S Fraitag, A Idbaih… - The Lancet, 2021 - thelancet.com
Histiocytoses constitute a heterogeneous group of rare disorders, characterised by
infiltration of almost any organ by myeloid cells with diverse macrophage or dendritic cell …

Histiocytoses: emerging neoplasia behind inflammation

J Haroche, F Cohen-Aubart, BJ Rollins… - The Lancet …, 2017 - thelancet.com
Histiocytoses are disorders characterised by inflammation and the accumulation of cells
derived from the monocyte and macrophage lineages, which results in tissue damage …

Systemic histiocytosis (Langerhans cell histiocytosis, Erdheim–Chester disease, Destombes–Rosai–Dorfman disease): from oncogenic mutations to inflammatory …

M Papo, F Cohen-Aubart, L Trefond, A Bauvois… - Current Oncology …, 2019 - Springer
Abstract Purpose of Review Provide an overview of recent progress in decoding the
pathogenesis and treatment of systemic histiocytoses. Recent Findings Advances in …

Histiocytic disorders

KL McClain, C Bigenwald, M Collin… - Nature Reviews …, 2021 - nature.com
The historic term 'histiocytosis' meaning 'tissue cell'is used as a unifying concept for
diseases characterized by pathogenic myeloid cells that share histological features with …

Diverse kinase alterations and myeloid-associated mutations in adult histiocytosis

J Chen, A Zhao, M Duan, H Cai, X Gao, T Liu, J Sun… - Leukemia, 2022 - nature.com
Histiocytosis are rare types of hematological tumors originating from dendritic cells or
macrophages. Comprehensive genomic analysis have uncovered a series of activating …

Natural history of histiocytosis-X

DH Berry, DL Becton - Hematology/Oncology Clinics of North America, 1987 - Elsevier
Natural History of Histiocytosis-X Page 1 Histiocytosis-X 0889–8588/87 3000 + 20 Natural
History of Histiocytosis-X Daisilee H. Berry, MD, * and David L. Becton, MD The natural history …

Langerhans cell histiocytosis

C Rodriguez-Galindo, CE Allen - Blood, The Journal of the …, 2020 - ashpublications.org
Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors
that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …

High prevalence of myeloid neoplasms in adults with non–Langerhans cell histiocytosis

M Papo, EL Diamond, F Cohen-Aubart… - Blood, The Journal …, 2017 - ashpublications.org
Erdheim-Chester disease (ECD) is a rare non–Langerhans cell histiocytosis that most
commonly affects adults and is driven by a high frequency of mutations in BRAF, MAP2K1 …

Molecular characterization of the histiocytoses: neoplasia of dendritic cells and macrophages

BH Durham - Seminars in Cell & Developmental Biology, 2019 - Elsevier
The systemic histiocytoses encompass a clinically heterogeneous group of disorders
leading to tissue damage secondary to the accumulation and infiltration of pathological cells …

Histiocytosis and the nervous system: from diagnosis to targeted therapies

F Cohen Aubart, A Idbaih, JF Emile, Z Amoura… - Neuro …, 2021 - academic.oup.com
Histiocytoses are heterogeneous hematopoietic diseases characterized by the accumulation
of CD68 (+) cells with various admixed inflammatory infiltrates. The identification of the …