Therapeutic applications of extracellular vesicles in inflammatory bowel disease

SH Kim, B Keum, S Kwak, J Byun, JM Shin… - International journal of …, 2024 - mdpi.com
The treatment landscape for inflammatory bowel disease (IBD) has undergone substantial
advancements with the introduction of biologics. However, a considerable number of …

[HTML][HTML] Extracellular Vesicles: Novel Potential Therapeutic Agents in Inflammatory Bowel Diseases

I Mignini, G Piccirilli, F Termite, M Paratore, G Esposto… - Cells, 2023 - mdpi.com
Patients affected by inflammatory bowel diseases (IBD) can nowadays benefit from a
growing number of pharmacological options. However, in moderate-to-severe cases, the …

Extracellular vesicles and their indispensable roles in pathogenesis and treatment of inflammatory bowel disease: A comprehensive review

L Chen, Q Ou, X Kou - Life Sciences, 2023 - Elsevier
Inflammatory bowel disease (IBD) is a global disease with rising incidence worldwide, and
its debilitating symptoms and dissatisfactory therapies have brought heavy burdens for …

[HTML][HTML] Extracellular vesicles-mediated interaction within intestinal microenvironment in inflammatory bowel disease

Q Shen, Z Huang, J Yao, Y Jin - Journal of advanced research, 2022 - Elsevier
Background The intestinal tract is a complicated ecosystem with dynamic homeostasis via
interaction of intestine and microbiota. Inflammatory bowel disease (IBD) is chronic intestinal …

Extracellular vesicles in inflammatory bowel disease: small particles, big players

M Valter, S Verstockt, JA Finalet Ferreiro… - Journal of Crohn's …, 2021 - academic.oup.com
Extracellular vesicles are nanovesicles released by many cell types into the extracellular
space. They are important mediators of intercellular communication, enabling the functional …

Extracellular vesicles with possible roles in gut intestinal tract homeostasis and IBD

X Chang, SL Wang, SB Zhao, YH Shi… - Mediators of …, 2020 - Wiley Online Library
The intestinal tract consists of various types of cells, such as epithelial cells, Paneth cells,
macrophages, and lymphocytes, which constitute the intestinal immune system and play a …

[HTML][HTML] Therapeutic application and potential mechanism of plant-derived extracellular vesicles in inflammatory bowel disease

J Li, T Luo, D Wang, Y Zhao, Y Jin, G Yang… - Journal of Advanced …, 2024 - Elsevier
Background Plant-derived extracellular vesicles (PDEVs) are membrane vesicles
characterized by a phospholipid bilayer as the basic skeleton that is wrapped by various …

[HTML][HTML] Extracellular vesicles: the next generation theranostic nanomedicine for inflammatory bowel disease

D Li, M Yang, J Xu, H Xu, M Zhu, Y Liang… - International journal …, 2022 - ncbi.nlm.nih.gov
The recent rapid development in the field of extracellular vesicles (EVs) based
nanotechnology has provided unprecedented opportunities for nanomedicine platforms. As …

[HTML][HTML] Extracellular Vesicles: A Crucial Player in the Intestinal Microenvironment and Beyond

S Wang, J Luo, H Wang, T Chen, J Sun, Q Xi… - International Journal of …, 2024 - mdpi.com
The intestinal ecological environment plays a crucial role in nutrient absorption and overall
well-being. In recent years, research has focused on the effects of extracellular vesicles …

Exosomes in inflammatory bowel disease: what have we learned so far?

H Wang, C Ye, Y Wu, P Yang, C Chen, Z Liu… - Current drug …, 2020 - ingentaconnect.com
Inflammatory bowel disease (IBD) is an immune-mediated chronic inflammatory disease.
Although the etiology is uncertain, there is marked disbalance of mucosal immune …