Variation in VEGFA and risk of cardiovascular disease in the UK Biobank

H Chen, X Lv, J Yang, Z Chen, W Qiao… - Frontiers in …, 2023 - frontiersin.org
Background: Cardiovascular disease (CVD) is an escalating global health crisis,
contributing significantly to worldwide mortality and morbidity. Dyslipidemia stands as a …

A common variant highly associated with plasma VEGFA levels also contributes to the variation of both LDL-C and HDL-C [S]

MG Stathopoulou, A Bonnefond, NC Ndiaye… - Journal of lipid …, 2013 - ASBMB
Vascular endothelial growth factor A (VEGFA) is among the most-significant stimulators of
angiogenesis. Its effect on cardiovascular diseases and on the variation of related risk …

[HTML][HTML] VEGF-A related SNPs: a cardiovascular context

JC Meza-Alvarado, RA Page, B Mallard… - Frontiers in …, 2023 - frontiersin.org
Cardiovascular diseases (CVDs) are the leading cause of death worldwide. Currently,
cardiovascular disease risk algorithms play a role in primary prevention. However, this is …

VEGF-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease.

P Davidsson, S Eketjäll, N Eriksson… - Cardiovascular …, 2023 - europepmc.org
Aims The vascular endothelial growth factor (VEGF) family is involved in pathophysiological
mechanisms underlying cardio vascular (CV) diseases. The aim of this study was to …

Identification of cis- and trans-Acting Genetic Variants Explaining Up to Half the Variation in Circulating Vascular Endothelial Growth Factor Levels

S Debette, S Visvikis-Siest, MH Chen… - Circulation …, 2011 - Am Heart Assoc
Rationale: Vascular endothelial growth factor (VEGF) affects angiogenesis, atherosclerosis,
and cancer. Although the heritability of circulating VEGF levels is high, little is known about …

Study of the Association between VEGF Polymorphisms and the Risk of Coronary Artery Disease in Koreans

EJ Ko, IJ Kim, JY Lee, HW Park, HS Park… - Journal of Personalized …, 2022 - mdpi.com
Coronary artery disease (CAD), a leading cause of death worldwide, has a complex etiology
comprising both traditional risk factors (type 2 diabetes, dyslipidemia, arterial hypertension …

Vascular endothelial growth factor-D plasma levels and VEGFD genetic variants are independently associated with outcomes in patients with cardiovascular disease

P Davidsson, S Eketjäll, N Eriksson… - Cardiovascular …, 2023 - academic.oup.com
Aims The vascular endothelial growth factor (VEGF) family is involved in pathophysiological
mechanisms underlying cardiovascular (CV) diseases. The aim of this study was to …

Six novel loci associated with circulating VEGF levels identified by a meta-analysis of genome-wide association studies

SH Choi, D Ruggiero, R Sorice, C Song, T Nutile… - PLoS …, 2016 - journals.plos.org
Vascular endothelial growth factor (VEGF) is an angiogenic and neurotrophic factor,
secreted by endothelial cells, known to impact various physiological and disease processes …

Association of rs6921438 A< G with serum vascular endothelial growth factor concentrations in patients with metabolic syndrome

H Ghazizadeh, A Avan, M Fazilati, M Azimi-Nezhad… - Gene, 2018 - Elsevier
Background Genome-wide association studies (GWAS) have identified common variants at
the Vascular-Endothelial-Growth-Factor (VEGF) gene locus, which appear to be associated …

Association of Genetically Predicted Levels of Circulating Blood Lipids with Coronary Artery Disease Incidence

HD Manikpurage, J Ricard, U Houessou, J Bourgault… - medRxiv, 2024 - medrxiv.org
Background: Estimating the genetic risk of coronary artery disease (CAD) is now possible by
aggregating data from genome-wide association studies (GWAS) into polygenic risk scores …