Metabolic syndrome (MetS) is a risk factor for type 2 diabetes mellitus and cardiovascular
disease. Obesity is a component of the metabolic syndrome. Several genetic variants are …

During the last decades, the prevalence of obesity has increased rapidly among young
people. A polymorphism in the promoter region of the IL6 gene (-174G/C), has been …

Elevated plasma interleukin-6 (IL-6) is associated with coronary heart disease (CHD),
impaired glucose tolerance (IGT), and type 2 diabetes (T2DM). We and others have …

Objective: To systematically investigate associations of single nucleotide polymorphisms
(SNPs) near the IL-6 (IL6) and IL-6 receptor (IL6R) genes with body fat mass, in support for …

Background Polymorphisms in genes encoding adiponectin (ADIPOQ) and interleukin-6
(IL6) have been associated with adiposity and obese-related phenotypes. This study …

Elevated levels of the pro‐inflammatory cytokine interleukin‐6 (IL‐6) have been associated
with cardiovascular risk factors. The objective of this study was to investigate potential …

Obesity represents an expansion of adipose tissue (AT) mass and is closely related to
insulin resistance and cardiovascular disease. Several hormonal signals have been shown …

Aims/hypothesis The cytokine interleukin 6 (IL-6) is an essential regulator of the acute phase
response associated with insulin-resistant states including type 2 diabetes and obesity …

Introduction. Visceral obesity, the central core of metabolic syndrome (MetS), is conceived
as the pathogenic basis of an increased cardiovascular burden and is related with changes …

Objective Low‐grade inflammation has been related to obesity, insulin resistance and the
metabolic syndrome. The Asp358Ala variant and the CA‐repeat polymorphism in the …