[HTML][HTML] LRP1B: a giant lost in cancer translation
C Príncipe, IJ Dionísio de Sousa, H Prazeres… - Pharmaceuticals, 2021 - mdpi.com
Low-density lipoprotein receptor-related protein 1B (LRP1B) is a giant member of the LDLR
protein family, which includes several structurally homologous cell surface receptors with a …
protein family, which includes several structurally homologous cell surface receptors with a …
[HTML][HTML] Expression of a recombinant full-length LRP1B receptor in human non-small cell lung cancer cells confirms the postulated growth-suppressing function of this …
AG Beer, C Zenzmaier, M Schreinlechner, J Haas… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Low-density lipoprotein (LDL) receptor-related protein 1B (LRP1B), a member of the LDL
receptor family, is frequently inactivated in multiple malignancies including lung cancer …
receptor family, is frequently inactivated in multiple malignancies including lung cancer …
Regulation of LRP-1 expression: make the point
H Emonard, L Théret, AH Bennasroune, S Dedieu - Pathologie Biologie, 2014 - Elsevier
The low-density lipoprotein receptor-related protein-1 (LRP-1) is a membrane receptor
displaying both scavenging and signaling functions. The wide variety of extracellular ligands …
displaying both scavenging and signaling functions. The wide variety of extracellular ligands …
[HTML][HTML] Ectodomains of the LDL Receptor-Related Proteins LRP1b and LRP4 Have Anchorage Independent Functions In Vivo
MF Dietrich, L van der Weyden, HM Prosser… - PLoS …, 2010 - journals.plos.org
Background The low-density lipoprotein (LDL) receptor gene family is a highly conserved
group of membrane receptors with diverse functions in developmental processes …
group of membrane receptors with diverse functions in developmental processes …
Normal Development and Fertility of Knockout Mice Lacking the Tumor Suppressor Gene LRP1b Suggest Functional Compensation by LRP1
P Marschang, J Brich, EJ Weeber… - … and cellular biology, 2004 - Taylor & Francis
LRP1b and the closely related LRP1 are large members of the low-density lipoprotein
receptor family. At the protein level LRP1b is 55% identical to LRP1, a multifunctional and …
receptor family. At the protein level LRP1b is 55% identical to LRP1, a multifunctional and …
[HTML][HTML] LRP1 expression in colon cancer predicts clinical outcome
C Boulagnon-Rombi, C Schneider, C Leandri… - Oncotarget, 2018 - ncbi.nlm.nih.gov
LRP1 (low-density lipoprotein receptor-related protein 1), a multifunctional endocytic
receptor, has recently been identified as a hub within a biomarker network for multi-cancer …
receptor, has recently been identified as a hub within a biomarker network for multi-cancer …
[HTML][HTML] The putative tumor suppressor LRP1B, a novel member of the low density lipoprotein (LDL) receptor family, exhibits both overlapping and distinct properties …
CX Liu, Y Li, LM Obermoeller-McCormick… - Journal of Biological …, 2001 - ASBMB
The low density lipoprotein receptor-related protein-deleted in tumor (LRP1B, initially
referred to as LRP-DIT) was cloned and characterized as a candidate tumor suppressor. It is …
referred to as LRP-DIT) was cloned and characterized as a candidate tumor suppressor. It is …
[HTML][HTML] Roles of low-density lipoprotein receptor-related protein 1 in tumors
P Xing, Z Liao, Z Ren, J Zhao, F Song, G Wang… - Chinese journal of …, 2016 - Springer
Low-density lipoprotein receptor-related protein 1 (LRP1, also known as CD91), a
multifunctional endocytic and cell signaling receptor, is widely expressed on the surface of …
multifunctional endocytic and cell signaling receptor, is widely expressed on the surface of …
Down expression of LRP1B promotes cell migration via RhoA/Cdc42 pathway and actin cytoskeleton remodeling in renal cell cancer
S Ni, J Hu, Y Duan, S Shi, R Li, H Wu, Y Qu… - Cancer science, 2013 - Wiley Online Library
The low‐density lipoprotein receptor‐related protein 1B (LRP 1B) is known as a putative
tumor suppressor. The decreased expression of LRP 1B has been involved in multiple …
tumor suppressor. The decreased expression of LRP 1B has been involved in multiple …
The roles of low‐density lipoprotein receptor‐related proteins 5, 6, and 8 in cancer: a review
Low‐density lipoprotein receptor (LDLR) has been an object of research since the 1970s
because of its role in various cell functions. The LDLR family members include LRP5, LRP6 …
because of its role in various cell functions. The LDLR family members include LRP5, LRP6 …