During the course of evolution, bacteria have developed an intimate relationship with
humans colonizing specific body sites at the interface with the body exterior and …

Advancing age is accompanied by changes in the gut microbiota characterised by a loss of
beneficial commensal microbes that is driven by intrinsic and extrinsic factors such as diet …

Gut microbiota is established during birth and evolves with age, mostly maintaining the
commensal relationship with the host. A growing body of clinical evidence suggests an …

Extrinsic factors, such as lifestyle and diet, are shown to be essential in the control of human
healthy aging, and thus, longevity. They do so by targeting at least in part the gut …

The microbiome plays a fundamental role in the maturation, function, and regulation of the
host-immune system from birth to old age. In return, the immune system has co-evolved a …

The development of human gut microbiota begins as soon as the neonate leaves the
protective environment of the uterus (or maybe in-utero) and is exposed to innumerable …

Changing demographics have made aging and age-related chronic diseases an enormous
and growing biomedical and societal challenge. The biological processes of aging may …

The changing physiology and lifestyle of elderly people affect the gut microbiota
composition, the changes of which can, in turn, affect the health maintenance of the ageing …

During aging the immune system (IS) undergoes remarkable changes that collectively are
known as immunosenescence. It is a multifactorial and dynamic phenomenon that affects …

An emerging central concept in evolutionary biology suggests that symbiosis is a universal
characteristic of living organisms that can help in understanding complex traits and …