The application of the powerful tool molecular biology has made it possible to ask questions
not only about hormone production and action but also to characterize many of the receptor …

Development of the pituitary gland and pituitary cell determination and specification depend
on the expression and interaction of signaling molecules and transcription factors in …

Many aspects of pituitary development have become better understood in the past two
decades. The signaling pathways regulating pituitary growth and shape have emerged, and …

The pituitary gland functions as a relay between the hypothalamus and peripheral target
organs that regulate basic physiological functions, including growth, the stress response …

The mammalian anterior pituitary gland is a compound endocrine organ that regulates
reproductive development and fitness, growth, metabolic homeostasis, the response to …

Defects in pituitary gland organogenesis are sometimes associated with congenital
anomalies that affect head development. Lesions in transcription factors and signaling …

Many common morphogenic, signaling and transcriptional hierarchy themes exist with
respect to a number of different model systems representing mammalian organogenesis …

Normal hypothalamopituitary development is closely related to that of the forebrain and is
dependent upon a complex genetic cascade of transcription factors and signaling molecules …

Our molecular understanding of growth hormone-induced signal transduction has improved
significantly over the past decades. At the same time, human population genetics and the …

The pituitary gland is a central endocrine organ regulating basic physiological functions,
including growth, the stress response, reproduction, metabolic homeostasis, and lactation …