Squamous-cell cancer of the head and neck (SCCHN) represents a heterogeneous disease
entity, with various etiological factors implicated in the genesis of distinct molecular subsets …

Development of head and neck squamous cell carcinoma (HNSCC) is characterized by
accumulation of mutations in several oncogenes and tumor suppressor genes. We have …

Head and neck squamous cell carcinoma (HNSCC) is a disease with significant morbidity
and mortality. The advancement of next‐generation sequencing technologies now enables …

The past decade has seen an unprecedented increase in our understanding of the biology
and etiology of head and neck squamous cell carcinomas (HNSCC). Genome-wide …

Objective To conduct high-throughput mutational analysis in 6 commonly used head and
neck cancer cell lines. Comprehensive mutation analysis of primary head and neck …

Despite advances in understanding the underlying genetics, squamous cell carcinoma of
the head and neck (SCCHN) remains a major health risk and one of the leading causes of …

The value of mutational profiling by targeted next-generation sequencing (NGS) for risk
stratification of patients with locally advanced oro-/hypopharyngeal carcinomas treated with …

Importance Recurrent and/or metastatic head and neck cancer is usually incurable.
Implementation of precision oncology for these patients has been limited by incomplete …

Despite improvements in functional outcomes attributable to advances in radiotherapy,
chemotherapy, surgical techniques, and imaging techniques, survival in head and neck …

Head and neck squamous cell carcinomas (HNSCC) arising from the oral cavity, pharynx,
and larynx constitute the 6 th most common human cancer. Human papillomavirus (HPV) …