All organisms contain thousands of proteins and peptides in their body fluids. A deeper
insight into the functional relevance of these polypeptides under different physiological and …

The introduction of fast, sensitive, and robust techniques for proteomic analysis into clinical
practice represents a major step toward a new diagnostic approach of body fluids. In …

Use of capillary electrophoresis coupled to mass spectrometry (CE-MS) technology in
proteome analysis has increased, with a focus on the identification of biomarker peptides in …

Proteome analysis has emerged as a powerful technology to decipher biological processes.
One of the main goals is to discover biomarkers for diseases from tissues and body fluids …

Capillary electrophoresis combined with mass spectrometry (CE‐MS) has been used for
several years for the investigation of proteins and peptides as biomarkers for diagnosis and …

Proteome analysis is now emerging as key technology for deciphering biological processes
and the discovery of biomarkers for diseases from tissues and body fluids. The complexity …

CE offers a low running cost, short separation time, and a high-resolution technique that
requires only a small amount of analyte. It has a wide variety of operation modes (CZE, CEC …

A major requirement in the application of proteins as clinical biomarkers is that they provide
a highly sensitive and specific result in disease assessment. Since single biomarkers are …

Clinical proteomics, a rapidly growing field, intends to use specific diagnostic
proteomic/peptidomic markers for initial diagnosis or prognosis of the progression of various …

The development of noninvasive methods for diagnosis and prognosis of many diseases still
remains a challenging task in clinical medicine. In recent years, protein separation and …