Procalcitonin for reduced antibiotic exposure in ventilator-associated pneumonia: a randomised study

D Stolz, N Smyrnios, P Eggimann… - European …, 2009 - Eur Respiratory Soc
In patients with ventilator-associated pneumonia (VAP), guidelines recommend antibiotic
therapy adjustment according to microbiology results after 72 h. Circulating procalcitonin …

[HTML][HTML] Usefulness of procalcitonin for the diagnosis of ventilator-associated pneumonia

CE Luyt, A Combes, C Reynaud, G Hekimian… - Intensive care …, 2008 - Springer
Objective To assess the predictive capacity for the diagnosis of ventilator-associated
pneumonia (VAP) of serum procalcitonin levels before and on the day it is suspected …

Procalcitonin kinetics as a prognostic marker of ventilator-associated pneumonia

CE Luyt, V Guérin, A Combes, JL Trouillet… - American journal of …, 2005 - atsjournals.org
We investigated the value of procalcitonin kinetics as a prognostic marker during ventilator-
associated pneumonia (VAP). This prospective, observational study was conducted in a …

Procalcitonin guidance of antibiotic therapy in community-acquired pneumonia: a randomized trial

M Christ-Crain, D Stolz, R Bingisser… - American journal of …, 2006 - atsjournals.org
Rationale: In patients with community-acquired pneumonia, guidelines recommend
antibiotic treatment for 7 to 21 d. Procalcitonin is elevated in bacterial infections, and its …

Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial

L Bouadma, CE Luyt, F Tubach, C Cracco, A Alvarez… - The Lancet, 2010 - thelancet.com
Background Reduced duration of antibiotic treatment might contain the emergence of
multidrug-resistant bacteria in intensive care units. We aimed to establish the effectiveness …

Prognostic value of procalcitonin in pneumonia: A systematic review and meta‐analysis

D Liu, L Su, W Guan, K Xiao, L Xie - Respirology, 2016 - Wiley Online Library
This meta‐analysis was performed to determine the accuracy of procalcitonin (PCT) in
predicting mortality in pneumonia patients with different pathogenic features and disease …

[PDF][PDF] The role of procalcitonin in adult patients with community-acquired pneumonia—a systematic review

P Berg, BØ Lindhardt - Dan Med J, 2012 - content.ugeskriftet.dk
ABSTRACT INTRODUCTION: Promising results in relation to severity assessment and
treatment of patients with communityacquired pneumonia (CAP) have recently been …

Procalcitonin algorithms for antibiotic therapy decisions: a systematic review of randomized controlled trials and recommendations for clinical algorithms

P Schuetz, V Chiappa, M Briel… - Archives of internal …, 2011 - jamanetwork.com
Previous randomized controlled trials suggest that using clinical algorithms based on
procalcitonin levels, a marker of bacterial infections, results in reduced antibiotic use without …

Procalcitonin usefulness for the initiation of antibiotic treatment in intensive care unit patients

N Layios, B Lambermont, JL Canivet… - Critical care …, 2012 - journals.lww.com
Objectives: To test the usefulness of procalcitonin serum level for the reduction of antibiotic
consumption in intensive care unit patients. Design: Single-center, prospective, randomized …

Effect of procalcitonin-guided treatment on antibiotic use and outcome in lower respiratory tract infections: cluster-randomised, single-blinded intervention trial

M Christ-Crain, D Jaccard-Stolz, R Bingisser… - The Lancet, 2004 - thelancet.com
Background Lower respiratory tract infections are often treated with antibiotics without
evidence of clinically relevant bacterial disease. Serum calcitonin precursor concentrations …