[HTML][HTML] Ebola virus disease: An emerging and re-emerging viral threat

M Rojas, DM Monsalve, Y Pacheco… - Journal of …, 2020 - Elsevier
The genus Ebolavirus from the family Filoviridae is composed of five species including
Sudan ebolavirus, Reston ebolavirus, Bundibugyo ebolavirus, Taï Forest ebolavirus, and …

Clinical features and pathobiology of Ebolavirus infection

AA Ansari - Journal of autoimmunity, 2014 - Elsevier
There has clearly been a deluge of international press coverage of the recent outbreak of
Ebolavirus in Africa and is partly related to the “fear factor” that comes across when one is …

Immunopathology of highly virulent pathogens: insights from Ebola virus

CA Zampieri, NJ Sullivan, GJ Nabel - Nature immunology, 2007 - nature.com
Ebola virus is a highly virulent pathogen capable of inducing a frequently lethal hemorrhagic
fever syndrome. Accumulating evidence indicates that the virus actively subverts both innate …

The pathogenesis of Ebola virus disease

L Baseler, DS Chertow, KM Johnson… - Annual Review of …, 2017 - annualreviews.org
For almost 50 years, ebolaviruses and related filoviruses have been repeatedly reemerging
across the vast equatorial belt of the African continent to cause epidemics of highly fatal …

Characterization of host immune responses in Ebola virus infections

G Wong, GP Kobinger, X Qiu - Expert review of clinical immunology, 2014 - Taylor & Francis
Ebola causes highly lethal hemorrhagic fever in humans with no licensed countermeasures.
Its virulence can be attributed to several immunoevasion mechanisms: an early inhibition of …

Ebola virus disease: epidemiology, clinical features, management, and prevention

E Nicastri, G Kobinger, F Vairo, C Montaldo… - Infectious Disease …, 2019 - id.theclinics.com
Ebola virus disease (EVD), also known as Ebola hemorrhagic fever or Ebola, is caused by
the Ebola virus (EBOV). EBOV is a linear, nonsegmented, single negative-stranded RNA …

New filovirus disease classification and nomenclature

JH Kuhn, T Adachi, NKJ Adhikari, JR Arribas… - Nature Reviews …, 2019 - nature.com
The recent large outbreak of Ebola virus disease (EVD) in Western Africa resulted in greatly
increased accumulation of human genotypic, phenotypic and clinical data, and improved our …

Ebola virus: A global public health menace: A narrative review

S Hasan, SA Ahmad, R Masood… - Journal of family …, 2019 - journals.lww.com
Ebola virus disease (EVD), a fatal viral hemorrhagic illness, is due to infection with the Ebola
virus of the Filoviridae family. The disease has evolved as a global public health menace …

Early immune responses accompanying human asymptomatic Ebola infections

EM Leroy, S Baize, P Debre… - Clinical & …, 2001 - academic.oup.com
In a recent study we identified certain asymptomatic individuals infected by Ebola virus
(EBOV) who mounted specific IgG and early and strong inflammatory responses. Here, we …

Human Ebola virus infection results in substantial immune activation

AK McElroy, RS Akondy, CW Davis… - Proceedings of the …, 2015 - National Acad Sciences
Four Ebola patients received care at Emory University Hospital, presenting a unique
opportunity to examine the cellular immune responses during acute Ebola virus infection …