Introduction Biologics serve as a cornerstone in psoriasis treatment, with low disease activity
or sometimes even clinical remission as a realistic treatment outcome. So far, it is unclear …

Background Psoriasis is an immune-mediated chronic inflammatory skin disorder for which
several targeted biologic therapies became available in the last 10 years. Data from patients …

Importance Biologics revolutionized the treatment of psoriasis. Biologics are given in a fixed
dose, but lower doses might be possible. Objective To investigate whether dose reduction …

Introduction In biologic therapy, dose modification in carefully selected patients when
psoriasis is in remission could reduce treatment costs and the risks associated with drug …

Dose reduction of biologics for psoriasis could contribute to more efficient use of these
expensive medicines. Evidence on opinions of patients with psoriasis regarding dose …

Introduction: Biologic medications increase dramatically the burden of a chronic and high
prevalent disease like psoriasis. The objective of the study was to quantify the use of dose …

Background Dose reduction of biologics for psoriasis is applied in daily practice, although
guidelines are lacking. Striving for clear criteria is important, as it leads to a consistent …

Background: Biologics are usually licensed according to the “one dose fits all” principle. It is
therefore suspected that a significant number of patients with psoriasis are overtreated …

Introduction Despite the large routine use of biologic drugs in psoriasis treatment, the
majority of studies do not take into consideration dose‐adjustment practice in 'real …

Dose reduction of biologics for psoriasis could contribute to lower drug exposure. This study
evaluated a one-step, tightly controlled, biologic dose reduction strategy in a prospective …