Advances on the anti-inflammatory activity of oleanolic acid and derivatives

X Zhang, H Wang, Y Xu, M Luan… - Mini Reviews in …, 2021 - ingentaconnect.com
Oleanolic acid can inhibit edema and exhibit obvious inhibitory activity to inflammatory by
activating of the pituitary-adrenal cortical system, inhibiting the synthesis or release of PGs …

The in vitro and in vivo study of oleanolic acid indole derivatives as novel anti-inflammatory agents: Synthesis, biological evaluation, and mechanistic analysis

J Jin, H He, X Zhang, R Wu, L Gan, D Li, Y Lu, P Wu… - Bioorganic …, 2021 - Elsevier
Oleanolic acid (OA) is a well-known natural product possessing many important
pharmacological activities; however, its weak bioactivities significantly restrict the potential …

Design, synthesis and anti-inflammatory evaluation of aloe-emodin derivatives as potential modulators of Akt, NF-κB and JNK signaling pathways

H Shang, J Guo, P Wang, L Li, Y Tian, X Li… - European journal of …, 2022 - Elsevier
To discover novel anti-inflammatory agents, a series of nitrogen-containing derivatives of
aloe-emodin were designed and synthesized. The anti-inflammatory activities of all …

Anti-inflammatory, anti-angiogenic and anti-nociceptive activities of 4-hydroxybenzaldehyde

EJ Lim, HJ Kang, HJ Jung, KH Kim… - Biomolecules & …, 2008 - koreascience.kr
The current work was designed to assess novel pharmacological activities of 4-
hydroxybenzaldehyde (HD), a major phenolic constituent of various natural products of plant …

Inflammation: a multidimensional insight on natural anti-inflammatory therapeutic compounds

K Bashir Dar, A Hussain Bhat, S Amin… - Current Medicinal …, 2016 - ingentaconnect.com
Derailed inflammation causes severe damage to the normal tissues resulting in various
pathological conditions such as auto-inflammatory disorders, neurodegenerative diseases …

Anti-inflammatory Effects of Oleanolic Acid on LPS-Induced Inflammation In Vitro and In Vivo

W Lee, EJ Yang, SK Ku, KS Song, JS Bae - Inflammation, 2013 - Springer
Oleanolic acid (OA) is a triterpenoid known for its anti-inflammatory and anti-cancer
properties; however, the anti-inflammatory effects of OA on lipopolysaccharide (LPS) …

Anti-inflammatory and analgesic potential of OA-DHZ; a novel semisynthetic derivative of dehydrozingerone

P Chibber, C Kumar, A Singh, SA Haq, I Ahmed… - International …, 2020 - Elsevier
Despite various advances in the arena of the current system of medicine, there are
numerous side effects associated with the therapeutics which essentially demand research …

[HTML][HTML] Efficient in vitro and in vivo anti-inflammatory activity of a diamine-PEGylated oleanolic acid derivative

F Jannus, M Medina-O'Donnell, VE Neubrand… - International Journal of …, 2021 - mdpi.com
Recent evidence has shown that inflammation can contribute to all tumorigenic states. We
have investigated the anti-inflammatory effects of a diamine-PEGylated derivative of …

Design, synthesis, molecular modelling, and biological evaluation of oleanolic acid-arylidene derivatives as potential anti-inflammatory agents

R Hassan Mir, G Godavari, NA Siddiqui… - Drug Design …, 2021 - Taylor & Francis
Full article: Design, Synthesis, Molecular Modelling, and Biological Evaluation of Oleanolic
Acid-Arylidene Derivatives as Potential Anti-Inflammatory Agents Skip to Main Content Taylor …

[HTML][HTML] Molecular mechanisms of anti-inflammatory phytochemicals

N Cruz-Martins - International Journal of Molecular Sciences, 2022 - mdpi.com
Naturally occurring bioactives, also known as phytochemicals, have been widely recognized
and researched owing to their multiple potentialities. Used since ancient times by …