A critical review on the opportunity to use placenta and innovative biomonitoring methods to characterize the prenatal chemical exposome
T Contini, R Béranger, L Multigner… - Environmental …, 2023 - ACS Publications
Adverse effects associated with chemical exposures during pregnancy include several
developmental and reproductive disorders. However, considering the tens of thousands of …
developmental and reproductive disorders. However, considering the tens of thousands of …
Analytical strategies to profile the internal chemical exposome and the metabolome of human placenta
As a non-invasive biological matrix, the placenta offers great and novel opportunities to
monitor fetal exposure to exogenous chemicals and their biotransformation products (the …
monitor fetal exposure to exogenous chemicals and their biotransformation products (the …
[HTML][HTML] Pregnancy-related maternal physiological adaptations and fetal chemical exposure
MT Vinnars, M Bixo, P Damdimopoulou - Molecular and Cellular …, 2023 - Elsevier
Prenatal life represents a susceptible window of development during which chemical
exposures can permanently alter fetal development, leading to an increased likelihood of …
exposures can permanently alter fetal development, leading to an increased likelihood of …
Developing novel in vitro methods for the risk assessment of developmental and placental toxicants in the environment
During pregnancy, the placenta is critical for the regulation of maternal homeostasis and
fetal growth and development. Exposures to environmental chemicals during pregnancy can …
fetal growth and development. Exposures to environmental chemicals during pregnancy can …
Environmental chemicals and adverse pregnancy outcomes: Placenta as a target and possible driver of pre-and postnatal effects
J Li, A Covaci, D Chen - Critical Reviews in Environmental Science …, 2023 - Taylor & Francis
Human placenta is key to fetal growth and development as it controls maternal-to-fetal
exchanges of endogenous and exogenous substances. Despite numerous studies have …
exchanges of endogenous and exogenous substances. Despite numerous studies have …
Review of the environmental prenatal exposome and its relationship to maternal and fetal health
Environmental chemicals comprise a major portion of the human exposome, with some
shown to impact the health of susceptible populations, including pregnant women and …
shown to impact the health of susceptible populations, including pregnant women and …
Fetal exposure to environmental chemicals; insights from placental perfusion studies
L Mathiesen, T Buerki-Thurnherr, J Pastuschek… - Placenta, 2021 - Elsevier
Introduction The burden of environmental chemicals in the human population is ubiquitous
and especially problematic in pregnancy due to potential exposure of the vulnerable fetus …
and especially problematic in pregnancy due to potential exposure of the vulnerable fetus …
Environmental toxicants and placental function
MS Bloom, M Varde, RB Newman - Best Practice & Research Clinical …, 2022 - Elsevier
The placenta is a temporary endocrine organ that facilitates gas, nutrient, and waste
exchange between maternal and fetal compartments, partially shielding the fetus from …
exchange between maternal and fetal compartments, partially shielding the fetus from …
Placental transfer of persistent organic pollutants and feasibility using the placenta as a non-invasive biomonitoring matrix
The placenta is a crucial organ for the supply of oxygen and nutritional elements from
mother to fetus. Several studies have reported evidence of the placental transfer of …
mother to fetus. Several studies have reported evidence of the placental transfer of …
[HTML][HTML] Integrative exposomic, transcriptomic, epigenomic analyses of human placental samples links understudied chemicals to preeclampsia
A Chao, J Grossman, C Carberry, Y Lai… - Environment …, 2022 - Elsevier
Background Environmental health research has recently undergone a dramatic shift, with
ongoing technological advancements allowing for broader coverage of exposure and …
ongoing technological advancements allowing for broader coverage of exposure and …