Exome sequencing identifies potentially druggable mutations in nasopharyngeal carcinoma
In this study, we first performed whole exome sequencing of DNA from 10 untreated and
clinically annotated fresh frozen nasopharyngeal carcinoma (NPC) biopsies and matched …
clinically annotated fresh frozen nasopharyngeal carcinoma (NPC) biopsies and matched …
The genomic landscape of nasopharyngeal carcinoma
DC Lin, X Meng, M Hazawa, Y Nagata, AM Varela… - Nature …, 2014 - nature.com
Nasopharyngeal carcinoma (NPC) has extremely skewed ethnic and geographic
distributions, is poorly understood at the genetic level and is in need of effective therapeutic …
distributions, is poorly understood at the genetic level and is in need of effective therapeutic …
[HTML][HTML] Hotspot mutations in common oncogenes are infrequent in nasopharyngeal carcinoma
N Jiang, N Liu, F Yang, Q Zhou, R Cui… - Oncology …, 2014 - spandidos-publications.com
Oncogene mutations contribute to carcinogenesis and can provide potential therapeutic
targets for clinical anticancer management. However, oncogene mutation patterns in …
targets for clinical anticancer management. However, oncogene mutation patterns in …
[HTML][HTML] Translational genomics of nasopharyngeal cancer
Nasopharyngeal carcinoma (NPC), also named the Cantonese cancer, is a unique cancer
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …
with strong etiological association with infection of the Epstein-Barr virus (EBV). With …
Molecular landscape and subtype-specific therapeutic response of nasopharyngeal carcinoma revealed by integrative pharmacogenomics
Nasopharyngeal carcinoma (NPC) is a malignant head and neck cancer type with high
morbidity in Southeast Asia, however the pathogenic mechanism of this disease is poorly …
morbidity in Southeast Asia, however the pathogenic mechanism of this disease is poorly …
Comprehensive genomic profiling of different subtypes of nasopharyngeal carcinoma reveals similarities and differences to guide targeted therapy
BACKGROUND To date, no targeted therapy has been approved for nasopharyngeal
carcinoma (NPC), and this underscores the need for an in‐depth understanding of clinically …
carcinoma (NPC), and this underscores the need for an in‐depth understanding of clinically …
Prognostic implications of a molecular classifier derived from whole‐exome sequencing in nasopharyngeal carcinoma
HY Wang, F Li, N Liu, XY Liu, XH Yang… - Cancer …, 2019 - Wiley Online Library
The aim of this study was to use whole‐exome sequencing to derive a molecular classifier
for nasopharyngeal carcinoma (NPC) and evaluate its clinical performance. We performed …
for nasopharyngeal carcinoma (NPC) and evaluate its clinical performance. We performed …
[HTML][HTML] Comparison of whole exome sequencing in circulating tumor cells of primitive and metastatic nasopharyngeal carcinoma
J Si, B Huang, G Lan, B Zhang, J Wei… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
Background Nasopharyngeal carcinoma (NPC) is one of the most common cancers. To
investigate the gene mutation profile of NPC patients, we performed whole exome …
investigate the gene mutation profile of NPC patients, we performed whole exome …
Exome and genome sequencing of nasopharynx cancer identifies NF-κB pathway activating mutations
Nasopharyngeal carcinoma (NPC) is an aggressive head and neck cancer characterized by
Epstein-Barr virus (EBV) infection and dense lymphocyte infiltration. The scarcity of NPC …
Epstein-Barr virus (EBV) infection and dense lymphocyte infiltration. The scarcity of NPC …
Oncogene mutational profile in nasopharyngeal carcinoma
ZC Zhang, S Fu, F Wang, HY Wang… - OncoTargets and …, 2014 - Taylor & Francis
Nasopharyngeal carcinoma (NPC) is a common tumor in Southern China, but the oncogene
mutational status of NPC patients has not been clarified. Using time-of-flight mass …
mutational status of NPC patients has not been clarified. Using time-of-flight mass …
相关搜索
- nasopharyngeal carcinoma exome sequencing
- nasopharyngeal carcinoma targeted therapy
- nasopharyngeal carcinoma hotspot mutations
- nasopharyngeal carcinoma therapeutic response
- tumor cells exome sequencing
- nasopharyngeal carcinoma tumor cells
- activating mutations genome sequencing
- nasopharyngeal carcinoma integrative pharmacogenomics
- nasopharyngeal carcinoma common oncogenes
- nasopharyngeal carcinoma molecular classifier
- nasopharyngeal carcinoma genomic landscape
- nasopharyngeal carcinoma similarities and differences
- nasopharyngeal carcinoma prognostic implications
- nasopharyngeal carcinoma molecular landscape