Ferroptosis, a cell death process driven by iron-dependent phospholipid peroxidation, has
been implicated in various diseases. There are two major surveillance mechanisms to …

Ferroptosis is widely involved in degenerative diseases in various tissues including kidney,
liver and brain, and is a targetable vulnerability in multiple primary and therapy-resistant …

Ferroptosis is an iron-dependent form of regulated cell death linking iron, lipid, and
glutathione levels to degenerative processes and tumor suppression. By performing a …

Ferroptosis is a form of regulated necrotic cell death controlled by glutathione peroxidase 4
(GPX4). At present, mechanisms that could predict sensitivity and/or resistance and that may …

Ferroptosis was first coined in 2012 to describe the form of regulated cell death (RCD)
characterized by iron‐dependent lipid peroxidation. To date, ferroptosis has been implicated …

Ferroptosis, a form of regulated cell death that is driven by iron-dependent phospholipid
peroxidation, has been implicated in multiple diseases, including cancer,–, degenerative …

Ferroptosis is a form of regulated cell death that is caused by the iron-dependent
peroxidation of lipids,. The glutathione-dependent lipid hydroperoxidase glutathione …

Ferroptosis has emerged as a crucial regulated cell death involved in a variety of
physiological processes or pathological diseases, such as tumor suppression. Though …

The accumulation of lipid peroxides is recognized as a determinant of the occurrence of
ferroptosis. However, the sensors and amplifying process of lipid peroxidation linked to …

Background Cancer is one of the major threats to human health and current cancer
therapies have been unsuccessful in eradicating it. Ferroptosis is characterized by iron …