The basic helix-loop-helix myogenic regulatory factors MyoD, Myf5, myogenin and MRF4
have critical roles in skeletal muscle development. Together with the Mef2 proteins and E …

The basic helix-loop-helix muscle regulatory factor (MRF) gene family encodes four distinct
muscle-specific transcription factors known as MyoD, myogenin, Myf-5, and MRF4. These …

Skeletal muscle development requires the coordinated expression of numerous transcription
factors to control the specification of mesodermal progenitor cells to a muscle fate and the …

The formation of skeletal muscle during vertebrate embryogenesis requires commitment of
mesodermal precursor cells to the skeletal muscle lineage, withdrawal of myoblasts from the …

The basic helix-loop-helix (bHLH) transcription factors—MyoD, Myf5, myogenin, and MRF4—
can each activate the skeletal muscle-differentiation program in transfection assays …

The myogenic regulatory factors (MRFs) form a family of basic helix–loop–helix transcription
factors consisting of Myf-5, MyoD, myogenin, and MRF4. The MRFs play key regulatory roles …

The myogenic basic helix-loop-helix (bHLH) proteins regulate both skeletal muscle
specification and differentiation: MyoD and Myf5 establish the muscle lineage, whereas …

Establishment of skeletal muscle lineages is controlled by the MyoD family of basic helix-
loop-helix (bHLH) transcription factors. The ability of these factors to initiate myogenesis is …

Abstract The Myogenic Regulatory Factors (MRFs) Myf5, MyoD, myogenin and MRF4 are
members of the basic helix-loop-helix family of transcription factors that control the …

Members of the MEF2 family of transcription factors are upregulated during skeletal muscle
differentiation and cooperate with the MyoD family of myogenic basic helix-loop-helix …