Treatment of injured donor lungs ex vivo to accelerate organ recovery and ameliorate
reperfusion injury could have a major impact in lung transplantation. We have recently …

BACKGROUND: The inhibition of cellular metabolism induced by hypothermia obviates the
possibility of substantial reparative processes occurring during organ preservation. The aim …

Background More than 80% of donor lungs are potentially injured and therefore not
considered suitable for transplantation. With the use of normothermic ex vivo lung perfusion …

Background Cold static preservation (CSP) at higher temperatures (10° C) has been
recently shown as an optimal strategy up to 24-36h of preservation. Here, we hypothesized …

OBJECTIVES: Ex vivo lung perfusion (EVLP) is a promising modality for the evaluation and
treatment of marginal donor lungs. The optimal timing of EVLP initiation and the potential for …

BACKGROUND: A donor lung shortage prevents patients from receiving life-saving
transplants. Ex-vivo lung perfusion (EVLP) is a viable means of expanding the donor pool by …

OBJECTIVE: Normothermic ex vivo lung perfusion is a novel method to evaluate and
improve the function of injured donor lungs. We reviewed our experience with 50 …

Background Ex vivo lung perfusion (EVLP) was primarily developed for evaluation of
impaired donor lungs. The good clinical results raise the question for its possible impact on …

Background We report the ability to extend lung preservation up to 24 hours (24H) by using
autologous whole donor blood circulating within an ex vivo lung perfusion (EVLP) system …

Donor shortage urges optimal use of all lungs available. Ex vivo lung perfusion (EVLP) is a
method to evaluate lung function before implantation. EVLP was performed in pigs to …