Functional characterization of AF-04, an afucosylated anti-MARV GP antibody

M Zhang, Y Zhang, H Wu, X Wang, H Zheng… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Marburg virus (MARV), one member of the Filoviridae family, cause sporadic outbreaks of
hemorrhagic fever with high mortality rates. No countermeasures are currently available for …

[PDF][PDF] Non-neutralizing antibodies from a Marburg infection survivor mediate protection by Fc-effector functions and by enhancing efficacy of other antibodies

PA Ilinykh, K Huang, RI Santos, P Gilchuk, BM Gunn… - Cell host & …, 2020 - cell.com
Marburg virus (MARV) and Ebola virus (EBOV) belong to the family Filoviridae. MARV
causes severe disease in humans with high fatality. We previously isolated a large panel of …

[HTML][HTML] A novel MARV glycoprotein-specific antibody with potentials of broad-spectrum neutralization to filovirus

Y Zhang, M Zhang, H Wu, X Wang, H Zheng, J Feng… - Elife, 2024 - elifesciences.org
Marburg virus (MARV) is one of the filovirus species that cause deadly hemorrhagic fever in
humans, with mortality rates up to 90%. Neutralizing antibodies represent ideal candidates …

Monoclonal antibody cocktail protects hamsters from lethal marburg virus infection

A Marzi, E Haddock, M Kajihara… - The Journal of …, 2018 - academic.oup.com
Marburg virus (MARV), family Filoviridae, causes Marburg hemorrhagic fever (MHF) in
humans and nonhuman primates with case fatality rates of up to 90%. There is no approved …

[HTML][HTML] Protective mAbs and cross-reactive mAbs raised by immunization with engineered Marburg virus GPs

ML Fusco, T Hashiguchi, R Cassan, JE Biggins… - PLoS …, 2015 - journals.plos.org
The filoviruses, which include the marburg-and ebolaviruses, have caused multiple
outbreaks among humans this decade. Antibodies against the filovirus surface glycoprotein …

Macaque antibodies targeting Marburg virus glycoprotein induced by multivalent immunization

BM Janus, R Wang, TE Cleveland IV… - Journal of …, 2024 - Am Soc Microbiol
Marburg virus infection in humans is associated with case fatality rates that can reach up to
90%, but to date, there are no approved vaccines or monoclonal antibody (mAb) …

[HTML][HTML] Discovery of common marburgvirus protective epitopes in a BALB/c mouse model

WV Kalina, KL Warfield, GG Olinger, S Bavari - Virology journal, 2009 - Springer
Background Marburg virus (MARV) causes acute hemorrhagic fever that is often lethal, and
no licensed vaccines are available for preventing this deadly viral infection. The immune …

[HTML][HTML] A novel and secure pseudovirus reporter system based assay for neutralizing and enhancing antibody assay against Marburg virus

J Bi, H Wang, H Pei, Q Han, N Feng, Q Wang… - Frontiers in …, 2022 - frontiersin.org
Marburg virus (MARV) is one of the principal members of the filovirus family, which can
cause fatal hemorrhagic fever in humans. There are currently no prophylactic and …

Generation and characterization of protective antibodies to Marburg virus

JW Froude, T Pelat, S Miethe, SE Zak, AZ Wec… - MAbs, 2017 - Taylor & Francis
Marburg virus (MARV) and Ebola virus (EBOV) have been a source of epidemics and
outbreaks for several decades. We present here the generation and characterization of the …

Novel mutations in Marburg virus glycoprotein associated with viral evasion from antibody mediated immune pressure

M Kajihara, E Nakayama, A Marzi… - Journal of General …, 2013 - microbiologyresearch.org
Marburg virus (MARV) and Ebola virus, members of the family Filoviridae, cause lethal
haemorrhagic fever in humans and non-human primates. Although the outbreaks are …