[HTML][HTML] Ameliorating effects of traditional Chinese medicine preparation, Chinese materia medica and active compounds on ischemia/reperfusion-induced cerebral …

K Sun, J Fan, J Han - Acta Pharmaceutica Sinica B, 2015 - Elsevier
Ischemic stroke and ischemia/reperfusion (I/R) injury induced by thrombolytic therapy are
conditions with high mortality and serious long-term physical and cognitive disabilities. They …

Effects and mechanisms of compound Chinese medicine and major ingredients on microcirculatory dysfunction and organ injury induced by ischemia/reperfusion

JY Han, Q Li, ZZ Ma, JY Fan - Pharmacology & therapeutics, 2017 - Elsevier
Microcirculation dysfunction and organ injury after ischemia and reperfusion (I/R) result from
a complex pathologic process consisting of multiple links, with metabolism impairment in the …

Traditional Chinese medicine use in the pathophysiological processes of intracerebral hemorrhage and comparison with conventional therapy

T Duan, L Li, Y Yu, T Li, R Han, X Sun, Y Cui… - Pharmacological …, 2022 - Elsevier
Intracerebral hemorrhage (ICH) refers to hemorrhage caused by non-traumatic vascular
rupture in the brain parenchyma, which is characterized by acute onset, severe illness, and …

Anti-inflammatory Effects of Traditional Chinese Medicines on Preclinical in vivo Models of Brain Ischemia-Reperfusion-Injury: Prospects for Neuroprotective Drug …

T Peng, Y Jiang, M Farhan, P Lazarovici… - Frontiers in …, 2019 - frontiersin.org
Acquired brain ischemia-and reperfusion-injury (IRI), including both Ischemic stroke (IS) and
Traumatic Brain injury (TBI), is one of the most common causes of disability and death in …

Classical active ingredients and extracts of Chinese herbal medicines: pharmacokinetics, pharmacodynamics, and molecular mechanisms for ischemic stroke

T Zhu, L Wang, Y Feng, G Sun… - Oxidative medicine and …, 2021 - Wiley Online Library
Stroke is a leading cause of death and disability worldwide, and approximately 87% of
cases are attributed to ischemia. The main factors that cause ischemic stroke include …

[HTML][HTML] New progress in the approaches for blood–brain barrier protection in acute ischemic stroke

Y Li, W Zhong, Z Jiang, X Tang - Brain research bulletin, 2019 - Elsevier
Ischemic stroke is a disease with high morbidity and mortality worldwide, which often places
an additional strain on families and society due to the poor prognosis. Blood brain-barrier …

The signaling pathways and targets of natural compounds from traditional Chinese medicine in treating ischemic stroke

XH Li, FT Yin, XH Zhou, AH Zhang, H Sun, GL Yan… - Molecules, 2022 - mdpi.com
Ischemic stroke (IS) is a common neurological disorder associated with high disability rates
and mortality rates. At present, recombinant tissue plasminogen activator (r-tPA) is the only …

[HTML][HTML] Therapeutic targets of neuroprotection and neurorestoration in ischemic stroke: Applications for natural compounds from medicinal herbs

T Zhu, L Wang, L Wang, Q Wan - Biomedicine & Pharmacotherapy, 2022 - Elsevier
Neuroprotective and neurorestorative therapy represent two major drug intervention
strategies for ischemic stroke. Multiple factors such as excitotoxicity, inflammation …

Angiogenesis in ischemic stroke and angiogenic effects of Chinese herbal medicine

SW Seto, D Chang, A Jenkins, A Bensoussan… - Journal of clinical …, 2016 - mdpi.com
Stroke is one of the major causes of death and adult disability worldwide. The underlying
pathophysiology of stroke is highly complicated, consisting of impairments of multiple …

Stroke therapy in traditional Chinese medicine (TCM): prospects for drug discovery and development

X Gong, NJ Sucher - Trends in pharmacological sciences, 1999 - cell.com
Brain injuries resulting from stroke are a major and increasing public health problem in both
developed and developing countries worldwide. China's extensive experience in the use of …