[PDF][PDF] Development of a novel frailty index to predict mortality in patients with end‐stage liver disease

JC Lai, KE Covinsky, JL Dodge, WJ Boscardin… - …, 2017 - Wiley Online Library
Cirrhosis is characterized by muscle wasting, malnutrition, and functional decline that confer
excess mortality not well quantified by the Model for End‐Stage Liver Disease (MELD) …

Changes in frailty are associated with waitlist mortality in patients with cirrhosis

JC Lai, JL Dodge, MR Kappus, MA Dunn, ML Volk… - Journal of …, 2020 - Elsevier
Background & Aims To date, studies evaluating the association between frailty and mortality
in patients with cirrhosis have been limited to assessments of frailty at a single time point …

The liver frailty index improves mortality prediction of the subjective clinician assessment in patients with cirrhosis

JC Lai, KE Covinsky, CE McCulloch… - Official journal of the …, 2018 - journals.lww.com
OBJECTIVES: Frailty, a critical determinant of health outcomes, is most commonly assessed
in patients with cirrhosis by general clinician assessment that is limited by its subjectivity. We …

[PDF][PDF] Standard assessments of frailty are validated predictors of mortality in hospitalized patients with cirrhosis

EB Tapper, D Finkelstein, MA Mittleman… - …, 2015 - Wiley Online Library
The risk of morbidity and mortality for hospitalized patients with cirrhosis is high and
incompletely captured by conventional indices. We sought to evaluate the predictive role of …

Frailty is associated with increased risk of cirrhosis disease progression and death

S Wang, R Whitlock, C Xu, S Taneja, S Singh… - …, 2022 - Wiley Online Library
Abstract Background and Aims The Liver Frailty Index (LFI) is a well‐studied tool that
evaluates frailty in patients with cirrhosis. Consisting of grip strength, chair stands, and …

Frailty associated with waitlist mortality independent of ascites and hepatic encephalopathy in a multicenter study

JC Lai, RS Rahimi, EC Verna, MR Kappus, MA Dunn… - Gastroenterology, 2019 - Elsevier
Background & Aims Frailty is associated with mortality in patients with cirrhosis. We
measured frailty using 3 simple tests and calculated Liver Frailty Index (LFI) scores for …

Frailty in advanced liver disease

R Laube, H Wang, L Park, JK Heyman… - Liver …, 2018 - Wiley Online Library
Prognostication of patients with cirrhosis is complex, depending on more than just the
severity of liver disease. Scores such as the model for end‐stage liver disease (MELD) and …

A rapid bedside screen to predict unplanned hospitalization and death in outpatients with cirrhosis: a prospective evaluation of the clinical frailty scale

P Tandon, N Tangri, L Thomas, L Zenith… - Official journal of the …, 2016 - journals.lww.com
OBJECTIVES: Screening tools to determine which outpatients with cirrhosis are at highest
risk forunplannedhospitalization are lacking. Frailty is a novel prognostic factor but …

[HTML][HTML] Frailty is independently associated with increased hospitalisation days in patients on the liver transplant waitlist

M Sinclair, E Poltavskiy, JL Dodge… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To investigate the impact of physical frailty on risk of hospitalisation in cirrhotic patients
on the liver transplant waitlist. METHODS Cirrhotics listed for liver transplantation at a single …

[HTML][HTML] Frailty predicts waitlist mortality in liver transplant candidates

JC Lai, S Feng, NA Terrault, B Lizaola… - American journal of …, 2014 - Elsevier
We aimed to determine whether frailty, a validated geriatric construct of increased
vulnerability to physiologic stressors, predicts mortality in liver transplant candidates …