The hypothesis that functional groups of neurons in whisker barrels are linked to a modular
organization of cortical vessels was tested. Endovascular casts demonstrated cortical …

How neuronal activity changes cerebral blood flow is of biological and practical importance.
The rodent whisker-barrel system has special merits as a model for studies of changes in …

The spatial resolution of hemodynamic-based neuroimaging techniques, including
functional magnetic resonance imaging, is limited by the degree to which neurons regulate …

Optical imaging slit spectroscopy is a powerful method for estimating quantitative changes in
cerebral haemodynamics, such as deoxyhaemoglobin, oxyhaemoglobin and blood volume …

Activation of the rat primary somatosensory barrel field (S1BF) is a commonly used model to
study the mechanisms of evoked coupled cortical blood flow changes. However, the …

The whisker-to-barrel cortex is widely used to study neurovascular coupling, but the cellular
basis that underlies the perfusion changes is still largely unknown. Here, we identified …

Post-ischemia angiogenesis and vascular plasticity help to restore blood flow to ischemic
tissue and likely benefit long-term functional recovery. Physical activity has been shown to …

Understanding neurovascular coupling is a prerequisite for the interpretation of results
obtained from modern neuroimaging techniques. This study investigated the hemodynamic …

Background and Purpose Many stroke models in rats are based on occlusion of the middle
cerebral artery, which supplies a significant portion of multifunctional cortical and deep …

Brain imaging techniques that use vascular signals to map changes in neuronal activity rely
on the coupling between electrophysiology and hemodynamics, a phenomenon referred to …