Oxytocin pathway genes: evolutionary ancient system impacting on human affiliation, sociality, and psychopathology
Oxytocin (OT), a nonapeptide signaling molecule originating from an ancestral peptide,
appears in different variants across all vertebrate and several invertebrate species …
appears in different variants across all vertebrate and several invertebrate species …
Oxytocin, stress and social behavior: neurogenetics of the human oxytocin system
R Kumsta, M Heinrichs - Current opinion in neurobiology, 2013 - Elsevier
The neuropeptide oxytocin has had key roles throughout mammalian evolution in the
regulation of complex social cognition and behaviors, such as attachment, parental care …
regulation of complex social cognition and behaviors, such as attachment, parental care …
Variation in the oxytocin receptor gene predicts brain region–specific expression and social attachment
Background Oxytocin (OXT) modulates several aspects of social behavior. Intranasal OXT is
a leading candidate for treating social deficits in patients with autism spectrum disorder, and …
a leading candidate for treating social deficits in patients with autism spectrum disorder, and …
Oxytocin receptor dynamics in the brain across development and species
R Vaidyanathan, EAD Hammock - Developmental …, 2017 - Wiley Online Library
Oxytocin (OXT) signaling through the OXT receptor plays a significant role in a variety of
physiological processes throughout the lifespan. OXT's effects depend on the tissue …
physiological processes throughout the lifespan. OXT's effects depend on the tissue …
Detection, processing and reinforcement of social cues: regulation by the oxytocin system
R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …
A common allele in the oxytocin receptor gene (OXTR) impacts prosocial temperament and human hypothalamic-limbic structure and function
The evolutionarily highly conserved neuropeptide oxytocin is a key mediator of social and
emotional behavior in mammals, including humans. A common variant (rs53576) in the …
emotional behavior in mammals, including humans. A common variant (rs53576) in the …
Oxytocin receptor expression patterns in the human brain across development
Oxytocin plays a vital role in social behavior and homeostatic processes, with animal models
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …
indicating that oxytocin receptor (OXTR) expression patterns in the brain influence behavior …
Oxytocin in the socioemotional brain: implications for psychiatric disorders
P Kirsch - Dialogues in clinical neuroscience, 2015 - Taylor & Francis
The neuropeptide oxytocin (OXT), highly conserved during evolution, is an important
modulator of social and emotional processes across many species. During the last decade …
modulator of social and emotional processes across many species. During the last decade …
Molecular basis of oxytocin receptor signalling in the brain: what we know and what we need to know
M Busnelli, B Chini - Behavioral pharmacology of neuropeptides: Oxytocin, 2018 - Springer
Oxytocin (OT), a hypothalamic neuropeptide involved in regulating the social behaviour of
all vertebrates, has been proposed as a treatment for a number of neuropsychiatric …
all vertebrates, has been proposed as a treatment for a number of neuropsychiatric …
[HTML][HTML] Epigenetic variability in the human oxytocin receptor (OXTR) gene: A possible pathway from early life experiences to psychopathologies
The human oxytocin (OXT) system is implicated in the regulation of complex social
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …
behaviors, as well as in psychopathologies characterized by social deficits. Emerging …