Engineering antioxidative cascade metal-phenolic nanozymes for alleviating oxidative stress during extracorporeal blood purification

Z Wei, G Peng, Y Zhao, S Chen, R Wang, H Mao… - ACS …, 2022 - ACS Publications
Oxidative stress is a compelling risk factor in chronic kidney diseases and is further
aggravated for individuals during extracorporeal blood purification, ultimately leading to …

Natural metal polyphenol nanozyme: free radical scavenging and antioxidation for the treatment of acute kidney injury

H Yuan, F Wang, Z Wang, D Gu, W Huang… - ACS Materials …, 2023 - ACS Publications
Acute kidney injury (AKI) is a severe renal dysfunction syndrome associated with high
morbidity and mortality. Excessive production of reactive oxygen/nitrogen species (RONS) is …

Integrating Pt nanoparticles with carbon nanodots to achieve robust cascade superoxide dismutase-catalase nanozyme for antioxidant therapy

Y Zhang, W Gao, Y Ma, L Cheng, L Zhang, Q Liu… - Nano Today, 2023 - Elsevier
Nanozymes, nanomaterials with intrinsic enzyme mimetic activity, have emerged and been
used in a broad range of applications yet are constrained with limited catalytic efficiency …

Ultrasmall copper-based nanoparticles for reactive oxygen species scavenging and alleviation of inflammation related diseases

T Liu, B Xiao, F Xiang, J Tan, Z Chen, X Zhang… - Nature …, 2020 - nature.com
Oxidative stress is associated with many acute and chronic inflammatory diseases, yet
limited treatment is currently available clinically. The development of enzyme-mimicking …

Engineering ultrasmall ferroptosis‐targeting and reactive oxygen/nitrogen species‐scavenging nanozyme for alleviating acute kidney injury

K Wang, Y Zhang, W Mao, W Feng, S Lu… - Advanced Functional …, 2022 - Wiley Online Library
Acute kidney injury (AKI) is a serious renal dysfunction syndromes, which predominantly
correlates with the excess production of endogenous reactive oxygen/nitrogen species …

Bioinspired copper single‐atom nanozyme as a superoxide dismutase‐like antioxidant for sepsis treatment

J Yang, R Zhang, H Zhao, H Qi, J Li, JF Li, X Zhou… - …, 2022 - Wiley Online Library
Sepsis is a systemic inflammatory response syndrome with high morbidity and mortality
mediated by infection‐caused oxidative stress. Early antioxidant intervention by removing …

Constructing multifunctional Cu single-atom nanozyme for synergistic nanocatalytic therapy-mediated multidrug-resistant bacteria infected wound healing

X Qiu, L Zhuang, J Yuan, H Wang, X Dong, S He… - Journal of Colloid and …, 2023 - Elsevier
Developing an effective strategy to combat multi-drug-resistant (MDR) bacteria and promote
wound healing without overuse of antibiotics remains an important and challenging goal …

Facile preparation of homogeneous copper nanoclusters exhibiting excellent tetraenzyme mimetic activities for colorimetric glutathione sensing and fluorimetric …

C Liu, Y Cai, J Wang, X Liu, H Ren, L Yan… - … applied materials & …, 2020 - ACS Publications
Nanozymes are artificial enzymes, which can substitute traditional biological enzymes for
multifield applications. However, to date, it remains challenging to search novel mimic …

[HTML][HTML] Clinically translatable gold nanozymes with broad spectrum antioxidant and anti-inflammatory activity for alleviating acute kidney injury

DY Zhang, T Tu, MR Younis, KS Zhu, H Liu, S Lei… - Theranostics, 2021 - ncbi.nlm.nih.gov
Rationale: Acute kidney injury (AKI) is associated with aberrant generation of oxidative
species and inflammation, leading to high mortality of in-hospitalized patients. Although N …

Atomically Dispersed Cu Nanozyme with Intensive Ascorbate Peroxidase Mimic Activity Capable of Alleviating ROS‐Mediated Oxidation Damage

Y Chen, H Zou, B Yan, X Wu, W Cao, Y Qian… - Advanced …, 2022 - Wiley Online Library
Ascorbate peroxidase (APX) as a crucial antioxidant enzyme has drawn attentions for its
utilization in preventing cells from oxidative stress responses by efficiently scavenging H2O2 …