The nasopharynx is the primary site of colonization by respiratory pathogen that constitutes
the port of entrance in the respiratory tract. The role of mucosal respiratory microbiota in …

Introduction: The burden of respiratory viral infections is a global public health concern with
significant mortality, morbidity, and economic impact. While Koch's postulate led to …

Background The bacterial communities of the nasopharynx play an important role in upper
respiratory tract infections (URTIs). Our study represents the first survey of the nasopharynx …

Background Infection by pathogenic viruses results in rapid epithelial damage and
significantly impacts on the condition of the upper respiratory tract, thus the effects of viral …

Background The microbiota of the upper respiratory tract is increasingly recognized as a
gatekeeper of respiratory health. Despite this, the microbiota of healthy adults remains …

Abstract Knowledge of whether and how respiratory microbiota composition can prime the
immune system and provide colonisation resistance, limiting consecutive pathobiont …

Our study is the first to compare the nasopharyngeal microbiota of pediatric pneumonia
patients and control children by 454 pyrosequencing. A distinct microbiota was associated …

Background Secondary bacterial infections are an important cause of morbidity and mortality
associated with influenza infections. As bacterial disease can be caused by a disturbance of …

Background. Influenza A virus (IAV) has had the highest morbidity globally over the past
decade. A growing number of studies indicate that the upper respiratory tract (URT) …

To improve our understanding of upper respiratory tract (URT) diseases and the underlying
microbial pathogenesis, a better characterization of the healthy URT microbiome is crucial …