Untapped potential of multicenter studies: a review of cardiovascular risk prediction models revealed inappropriate analyses and wide variation in reporting
L Wynants, DM Kent, D Timmerman… - … and prognostic research, 2019 - Springer
Background Clinical prediction models are often constructed using multicenter databases.
Such a data structure poses additional challenges for statistical analysis (clustered data) but …
Such a data structure poses additional challenges for statistical analysis (clustered data) but …
Comparisons of established risk prediction models for cardiovascular disease: systematic review
Objective To evaluate the evidence on comparisons of established cardiovascular risk
prediction models and to collect comparative information on their relative prognostic …
prediction models and to collect comparative information on their relative prognostic …
Does ignoring clustering in multicenter data influence the performance of prediction models? A simulation study
L Wynants, Y Vergouwe, S Van Huffel… - … methods in medical …, 2018 - journals.sagepub.com
Clinical risk prediction models are increasingly being developed and validated on
multicenter datasets. In this article, we present a comprehensive framework for the …
multicenter datasets. In this article, we present a comprehensive framework for the …
The roles of predictors in cardiovascular risk models-a question of modeling culture?
C Wallisch, A Agibetov, D Dunkler, M Haller… - BMC Medical Research …, 2021 - Springer
Background While machine learning (ML) algorithms may predict cardiovascular outcomes
more accurately than statistical models, their result is usually not representable by a …
more accurately than statistical models, their result is usually not representable by a …
External validation of two Framingham cardiovascular risk equations and the pooled cohort equations: a nationwide registry analysis
Background Cardiovascular prevention guidelines advocate the use of statistical risk
equations to predict individual cardiovascular risk. However, predictive accuracy and clinical …
equations to predict individual cardiovascular risk. However, predictive accuracy and clinical …
Prediction models for cardiovascular disease risk in the general population: systematic review
Objective To provide an overview of prediction models for risk of cardiovascular disease
(CVD) in the general population. Design Systematic review. Data sources Medline and …
(CVD) in the general population. Design Systematic review. Data sources Medline and …
Impact of sample size on the stability of risk scores from clinical prediction models: a case study in cardiovascular disease
Background Stability of risk estimates from prediction models may be highly dependent on
the sample size of the dataset available for model derivation. In this paper, we evaluate the …
the sample size of the dataset available for model derivation. In this paper, we evaluate the …
Modelling of longitudinal data to predict cardiovascular disease risk: a methodological review
D Stevens, DA Lane, SL Harrison, GYH Lip… - BMC medical research …, 2021 - Springer
Objective The identification of methodology for modelling cardiovascular disease (CVD) risk
using longitudinal data and risk factor trajectories. Methods We screened MEDLINE-Ovid …
using longitudinal data and risk factor trajectories. Methods We screened MEDLINE-Ovid …
Validation of two Framingham cardiovascular risk prediction algorithms in an Australian population: the 'old'versus the 'new'Framingham equation
Background Multivariable risk prediction equations attempt to quantify an individual's
cardiovascular risk. Those borne from the Framingham Heart Study remain the most well …
cardiovascular risk. Those borne from the Framingham Heart Study remain the most well …
Laboratory-based versus non-laboratory-based World Health Organization risk equations for assessment of cardiovascular disease risk
Background The WHO model has laboratory-based and non-laboratory-based versions for
10-year risk prediction of cardiovascular diseases. Due to the fact that in some settings …
10-year risk prediction of cardiovascular diseases. Due to the fact that in some settings …