Chondroitin sulphate proteoglycans (CSPG s) are extracellular matrix molecules whose
inhibitory activity is attenuated by the enzyme chondroitinase ABC (C h ABC). Here we …

Degradation of extracellular matrix chondroitin sulphate proteoglycans (CSPGs) using
Chondroitinase ABC (ChABC) is a promising strategy for the treatment of spinal cord injury …

Chondroitin sulfate proteoglycans (CSPGs) are inhibitory extracellular matrix molecules that
are upregulated after CNS injury. Degradation of CSPGs using the enzyme chondroitinase …

Chondroitinase ABC (ChABC) in combination with rehabilitation has been shown to promote
functional recovery in acute spinal cord injury. For clinical use, the optimal treatment window …

In spinal cord injury, the injury could trigger some inhibitory signal cascades to promote
chondroitin sulfate proteoglycans (CSPGs), the structures of scar tissues, formation. CSPGs …

Chondroitin sulfate proteoglycans (CSPGs) are upregulated in the central nervous system
following injury. Chondroitin sulfate glycosaminoglycan (CS GAG) side chains substituted on …

Growth-inhibitory chondroitin sulfate proteoglycans (CSPG) are a primary target for
therapeutic strategies after spinal cord injury because of their contribution to the inhibitory …

Chondroitin sulfate proteoglycans (CSPGs) are glial scar-associated molecules considered
axonal regeneration inhibitors and can be digested by chondroitinase ABC (ChABC) to …

Background There is currently no effective treatment for promoting regeneration of injured
nerves in patients who have sustained injury to the central nervous system such as spinal …

Chondroitin sulfate proteoglycans (CSPGs) inhibit axonal growth, and treatment with
chondroitinase ABC promotes axonal regeneration in some models of central nervous …