Enzyme-Responsive COF-based thiol-targeting nanoinhibitor for curing bacterial infections
X Wang, B Sun, Z Ye, W Zhang, W Xu… - … Applied Materials & …, 2022 - ACS Publications
Pathogen infections impose severe challenges in clinical practice, especially for patients
infected with antibiotic-resistant microbes. The thioredoxin (Trx) system in Gram-positive …
infected with antibiotic-resistant microbes. The thioredoxin (Trx) system in Gram-positive …
Metal–Organic Framework‐Derived Homologous Sulfide Heterojunction for Robust Enzyme‐Like Self‐Driven Bacteria‐Killing through Enhanced Electron Transfer
Infectious diseases caused by various bacteria pose a serious threat to human health, and
the emergence of drug‐resistant bacteria has forced humans to develop new and effective …
the emergence of drug‐resistant bacteria has forced humans to develop new and effective …
Hollow cobalt sulfide nanospheres with highly enzyme-like antibacterial activities to accelerate infected wound healing
R Wu, Z Liu, Y Huang, L Huang, J Wang… - Bioconjugate …, 2023 - ACS Publications
The emergence of nanozymes presents a promising alternative to antibiotics for reactive
oxygen species-mediated broad-spectrum antimicrobial purposes, but nanozymes still face …
oxygen species-mediated broad-spectrum antimicrobial purposes, but nanozymes still face …
[HTML][HTML] Gold (I) selenium N-heterocyclic carbene complexes as potent antibacterial agents against multidrug-resistant gram-negative bacteria via inhibiting …
X Chen, S Sun, S Huang, H Yang, Q Ye, L Lv, Y Liang… - Redox Biology, 2023 - Elsevier
Abstract Multidrug-resistant (MDR) Gram-negative bacteria have become a global threat to
human life and health, and novel antibiotics are urgently needed. The thioredoxin (Trx) …
human life and health, and novel antibiotics are urgently needed. The thioredoxin (Trx) …
Sprayable CeCuOx Nanocatalytic Gel for Synergistic Antibacterial Therapy
M Xie, Z Wei, Z Niu, H Xu, Y Guo, J Huang… - ACS Applied Nano …, 2023 - ACS Publications
The bacterial microenvironment-activated nanocatalytic antibacterial strategy has attracted
extensive attention owing to the high specificity to eliminate pathogens, which provides …
extensive attention owing to the high specificity to eliminate pathogens, which provides …
Designing Single‐Atom Active Sites on sp2‐Carbon Linked Covalent Organic Frameworks to Induce Bacterial Ferroptosis‐Like for Robust Anti‐Infection Therapy
B Sun, X Wang, Z Ye, J Zhang, X Chen… - Advanced …, 2023 - Wiley Online Library
With the threat posed by drug‐resistant pathogenic bacteria, developing non‐antibiotic
strategies for eradicating clinically prevalent superbugs remains challenging. Ferroptosis is …
strategies for eradicating clinically prevalent superbugs remains challenging. Ferroptosis is …
Polymetallic Hybrid Nanoplatform with Hyperthermia‐Amplified Dual Enzyme‐Like Activities for Efficient Speeded‐Up Bacterially Infected Wound Healing
Antibiotic‐independent artificial nanozymes exhibit excellent biocatalytic activity, and can
generate sufficient reactive oxygen species (ROS) for potential applications in the field of …
generate sufficient reactive oxygen species (ROS) for potential applications in the field of …
Biomimetic metal–organic framework composite-mediated cascade catalysis for synergistic bacteria killing
X Cheng, S Zhang, H Liu, H Chen, J Zhou… - … applied materials & …, 2020 - ACS Publications
Encapsulating nanoparticles/biomolecules into metal–organic freamworks (MOFs) has
proven to be highly effective in creating new functions during their applications. However, it …
proven to be highly effective in creating new functions during their applications. However, it …
Novel gold (III)-dithiocarbamate complex targeting bacterial thioredoxin reductase: Antimicrobial activity, synergy, toxicity, and mechanistic insights
C Ratia, V Ballén, Y Gabasa, RG Soengas… - Frontiers in …, 2023 - frontiersin.org
Introduction Antimicrobial resistance is a pressing global concern that has led to the search
for new antibacterial agents with novel targets or non-traditional approaches. Recently …
for new antibacterial agents with novel targets or non-traditional approaches. Recently …
An optimally designed engineering exosome–reductive COF integrated nanoagent for synergistically enhanced diabetic fester wound healing
B Sun, F Wu, X Wang, Q Song, Z Ye… - Small, 2022 - Wiley Online Library
Oxidative stress and local overactive inflammation have been considered major obstacles in
diabetic wound treatment. Although antiphlogistic tactics have been reported widely, they …
diabetic wound treatment. Although antiphlogistic tactics have been reported widely, they …