Biomedical applications of macrocyclic ligand complexes

RE Mewis, SJ Archibald - Coordination Chemistry Reviews, 2010 - Elsevier
Macrocyclic chelators can form highly stable complexes with transition metals and
lanthanides. In this review, the recent advances towards biomedical applications of …

Rare earth complexes with neutral macrocyclic ligands

JCG Bünzli, D Wessner - Coordination chemistry reviews, 1984 - Elsevier
To help understand biological processes, chemists often design abiotic systems that
reproduce one, or preferentially, some of the features of these processes. To achieve this …

Solution chemistry of lanthanide macrocyclic complexes

F Arnaud-Neu - Chemical Society Reviews, 1994 - pubs.rsc.org
Macrocyclic receptors define a hydrophilic cavity in which an ionic substrate like a metal ion
can nest and be shielded from the environment by its lipophilic envelope.'Accordingly, they …

Radiolabeling and in vivo behavior of copper-64-labeled cross-bridged cyclam ligands

X Sun, M Wuest, GR Weisman, EH Wong… - Journal of medicinal …, 2002 - ACS Publications
Macrocyclic chelators and their metal complexes have widespread applications in the
biomedical sciences, including radiopharmaceutical chemistry. The use of copper …

Advancing chelation strategies for large metal ions for nuclear medicine applications

A Hu, JJ Wilson - Accounts of chemical research, 2022 - ACS Publications
Conspectus Nuclear medicine leverages radioisotopes of a wide range of elements, a
significant portion of which are metals, for the diagnosis and treatment of disease. To …

Design and synthesis of macrocyclic ligands and their complexes of lanthanides and actinides

V Alexander - Chemical reviews, 1995 - ACS Publications
Coordination chemistry of macrocyclic ligands has been a fascinating area of current
researchinterest to theinorganic chemists all over the world. The continued interest and …

Metal complexes as diagnostic tools

DE Reichert, JS Lewis, CJ Anderson - Coordination Chemistry Reviews, 1999 - Elsevier
This review summarizes some of the developments of metal complexes and metal-complex-
bioconjugates for the diagnosis of disease states that have occurred over the past 10 years …

Synthesis, Cu (ii) complexation, 64 Cu-labeling and biological evaluation of cross-bridged cyclam chelators with phosphonate pendant arms

R Ferdani, DJ Stigers, AL Fiamengo, L Wei… - Dalton …, 2012 - pubs.rsc.org
A new class of cross-bridged cyclam-based macrocycles featuring phosphonate pendant
groups has been developed. 1, 4, 8, 11-tetraazacyclotetradecane-1, 8-di …

[引用][C] Small coordination complexes as radiopharmaceuticals for cancer targeting

PJ Blower - Transition metal chemistry, 1997 - Springer
To find radionuclides with suitable nuclear properties (half-life, type of emissions and their
range in tissues) for in vivo medical use, one must select from the widest possible choice of …

Matching chelators to radiometals for radiopharmaceuticals

EW Price, C Orvig - Chemical Society Reviews, 2014 - pubs.rsc.org
Radiometals comprise many useful radioactive isotopes of various metallic elements. When
properly harnessed, these have valuable emission properties that can be used for …