Background Activation of the farnesoid X receptor (FXR) reduces renal inflammation, but the
underlying mechanisms remain elusive. Neutrophil extracellular traps (NETs) are webs of …

Farnesoid X receptor (FXR) activation reduces renal inflammation, but the underlying
mechanisms remain elusive. Neutrophil extracellular traps (NETs) are webs of DNA formed …

Purpose We investigated the role of farnesoid X receptor (FXR), a ligand‐dependent
transcription factor, in renal ischaemia‐reperfusion (I/R) injury. Materials and Methods We …

The prevalence of kidney diseases has been increasing worldwide due to the aging
population and has results in an increased socioeconomic burden as well as increased …

Farnesoid X receptor (FXR) activation has been reported to reduce inflammation and
oxidative stress. Because both inflammation and oxidative stress are critical for tissue …

Background End-stage renal disease is primarily caused by diabetic kidney disease (DKD).
The Farnesoid X receptor (FXR), a member of the nuclear receptor superfamily, has anti …

The age-associated functional decline of the kidney is accompanied by structural changes
including glomerular sclerosis and interstitial fibrosis. Aging kidneys also exhibit increased …

Farnesoid X receptor (FXR) is a nuclear receptor that has emerged as a key regulator in the
maintenance of hepatic steatosis, inflammation, and fibrosis. However, the role of FXR in …

Aim: To understand whether O 2 delivery mediated by erythrocyte S1P is involved in tissue
macrophage polarization and fibrosis. Methods and Results: Genetic ablation of erythrocyte …

The farnesoid X receptor (FXR) is a ligand-activated transcription factor belonging to the
nuclear receptor superfamily. FXR is mainly expressed in liver and small intestine, where it …