The Duffy protein, a transmembrane molecule, functions as a receptor for various
chemokines and facilitates attachment between the reticulocyte and the Plasmodium Duffy …

Background Plasmodium vivax infection is known to be rare in West/Central Africa, the most
accepted explanation being the lack of expression of erythroid Duffy antigen in the local …

Background Duffy blood group polymorphisms are important in areas where Plasmodium
vivax is present because this surface antigen is thought to act as a key receptor for this …

Objectives Plasmodium vivax malaria was thought to be rare in Africans who lack the Duffy
blood group antigen expression. However, recent studies indicate that P. vivax can infect …

Resistance to Plasmodium vivax blood-stage infection has been widely recognised to result
from absence of the Duffy (Fy) blood group from the surface of red blood cells (RBCs) in …

Background The increase in detections of Plasmodium vivax infection in Duffy-negative
individuals in Africa has challenged the dogma establishing the unique P. vivax Duffy …

Negative Duffy expression on the surface of human red blood cells was believed to be a
barrier for Plasmodium vivax infection in most Africans. However, P. vivax has been …

Background Recent studies from different malaria-endemic regions including western Africa
have now shown that Plasmodium vivax can infect red blood cells (RBCs) and cause clinical …

The Duffy protein, a transmembrane molecule, acts as a receptor for various chemokines
and facilitates binding between reticulocytes and the Plasmodium Duffy antigen binding …

Background There is large body of evidence that states that invasion of Plasmodium vivax
requires the Duffy antigen, but the universality of this specificity is certainly now under …