Liver transplantation is currently recognized as the only effective therapeutic option for end-
stage liver disease. Hepatic ischemia–reperfusion injury (IRI) remains a major cause of graft …

Reactive oxygen species (ROS) related oxidative stress causes an inflammatory storm and
massive hepatocyte necrosis in acute liver injury (ALI). Necrotic hepatocytes trigger an …

Hepatic ischemia-reperfusion injury (IRI), which mainly results from excessive reactive
oxygen species (ROS) generated by a reperfusion burst of oxygen, has long been a major …

Reactive oxygen and nitrogen species (RONS) are key signaling molecules that play an
important role in the progression of inflammatory diseases. Although various antioxidants …

Background Nonspecific liver uptake of nanomaterials after intravenous injection has
hindered nanomedicine for clinical translation. However, nanomaterials' propensity for liver …

Hepatic ischemia-reperfusion injury (IRI) is a common pathological process during
hepatectomy and liver transplantation and the two primary reasons for hepatic IRI are …

Background Hepatic ischemia-reperfusion injury (HIRI) is a pathophysiological process
during liver transplantation, characterized by insufficient oxygen supply and subsequent …

Acute liver injury (ALI) could severely destroy the liver function and cause inevitable damage
to human health. Studies have demonstrated that excessive reactive oxygen species (ROS) …

The mononuclear phagocyte system (MPS, eg, liver, spleen) is often treated as a “blackbox”
by nanoresearchers in translating nanomedicines. Often, most of the injected nanomaterials …

Hepatic ischemia–reperfusion injury (HIRI), which is a common pathophysiological process
that occurs in hepatectomy, affects the survival and prognosis of patients. In this study, we …