Collagen-based scaffolds: An auspicious tool to support repair, recovery, and regeneration post spinal cord injury

AT Mneimneh, MM Mehanna - International Journal of Pharmaceutics, 2021 - Elsevier
Spinal cord injury (SCI) is a perplexing traumatic disease that habitually gives ride to
permanent disability, motor, and sensory impairment. Despite the existence of several …

Biomaterial scaffolds used for the regeneration of spinal cord injury (SCI)

M Kim, SR Park, BH Choi - 2014 - digitum.um.es
This review presents a summary of various types of scaffold biomaterials used alone or
together with therapeutic drugs and cells to regenerate spinal cord injury (SCI). The …

Biomaterials combined with cell therapy for treatment of spinal cord injury

Š Kubinová, E Syková - Regenerative medicine, 2012 - Future Medicine
Spinal cord injury (SCI) is a devastating traumatic injury resulting in paralysis or sensory
deficits due to tissue damage and the poor ability of axons to regenerate across the lesion …

Collagen for brain repair: therapeutic perspectives

B Ucar, C Humpel - Neural regeneration research, 2018 - journals.lww.com
Biomaterials have increasingly become a focus of research on neuroprotection and
neuroregeneration. Collagen, in terms of brain repair, presents many advantages such as …

Polymer scaffolds facilitate spinal cord injury repair

Q Zhang, B Shi, J Ding, L Yan, JP Thawani, C Fu… - Acta biomaterialia, 2019 - Elsevier
During the past decades, improving patient neurological recovery following spinal cord
injury (SCI) has remained a challenge. An effective treatment for SCI would not only reduce …

A combinatorial approach for spinal cord injury repair using multifunctional collagen-based matrices: development, characterization and impact on cell adhesion and …

ZB Ahi, RC Assuncao-Silva, AJ Salgado… - Biomedical …, 2020 - iopscience.iop.org
Spinal cord injury is a devastating condition of the central nervous system, in which
traditional treatments are largely ineffective due to the complex nature of the injured tissue …

Current concepts of biomaterial scaffolds and regenerative therapy for spinal cord injury

H Suzuki, Y Imajo, M Funaba, H Ikeda… - International Journal of …, 2023 - mdpi.com
Spinal cord injury (SCI) is a catastrophic condition associated with significant neurological
deficit and social and financial burdens. It is currently being managed symptomatically, with …

The role of biomaterials in peripheral nerve and spinal cord injury: a review

B Kaplan, S Levenberg - International journal of molecular sciences, 2022 - mdpi.com
Peripheral nerve and spinal cord injuries are potentially devastating traumatic conditions
with major consequences for patients' lives. Severe cases of these conditions are currently …

A novel composite type I collagen scaffold with micropatterned porosity regulates the entrance of phagocytes in a severe model of spinal cord injury

S Snider, A Cavalli, F Colombo… - … Research Part B …, 2017 - Wiley Online Library
Traumatic spinal cord injury (SCI) is a damage to the spinal cord that results in loss or
impaired motor and/or sensory function. SCI is a sudden and unexpected event …

Role and prospects of regenerative biomaterials in the repair of spinal cord injury

S Liu, YY Xie, B Wang - Neural regeneration research, 2019 - journals.lww.com
Axonal junction defects and an inhibitory environment after spinal cord injury seriously
hinder the regeneration of damaged tissues and neuronal functions. At the site of spinal cord …