Objective: Acute respiratory distress syndrome is characterized by collapse of gravitationally
dependent lung regions that usually diverts tidal ventilation toward nondependent regions …

Rationale: Tidal volume and plateau pressure limitation decreases mortality in acute
respiratory distress syndrome. Computed tomography demonstrated a small, normally …

Objective: Low tidal volume ventilation lowers mortality in the acute respiratory distress
syndrome. Previous studies reported poor low tidal volume ventilation implementation. We …

Objective: To evaluate perceived attitudes, knowledge, and behaviors regarding the use of
low tidal volume ventilation in acute respiratory distress syndrome among physicians …

Purpose: To study the effect of two tidal volumes on gas exchange, lung mechanics, and
hemodynamics in 12 patients with acute respiratory distress syndrome (ARDS) within the …

Objective: To assess the effects of step-changes in tidal volume on work of breathing during
lung-protective ventilation in patients with acute lung injury (ALI) or the acute respiratory …

Rationale: Reducing tidal volume decreases mortality in acute respiratory distress syndrome
(ARDS). However, the effect of the timing of low tidal volume ventilation is not well …

Objectives: A recent randomized trial of mechanical ventilation in acute lung injury
(ALI)/adult respiratory distress syndrome (ARDS) demonstrated a 22% relative reduction in …

The ARDSNet trial revealed that the use of a smaller tidal volume (VT) reduced mortality by
22%. However, three earlier studies that lowered VT did not find a decrease in mortality. We …

Objective: To determine the usual practice for setting tidal volume and other ventilatory
parameters in patients with acute respiratory distress syndrome (ARDS) in the late 1990s …