Role of macrophages during skeletal muscle regeneration and hypertrophy—Implications for immunomodulatory strategies

C Bernard, A Zavoriti, Q Pucelle… - Physiological …, 2022 - Wiley Online Library
Skeletal muscle is a plastic tissue that regenerates ad integrum after injury and adapts to
raise mechanical loading/contractile activity by increasing its mass and/or myofiber size, a …

From skeletal muscle damage and regeneration to the hypertrophy induced by exercise: what is the role of different macrophage subsets?

ALA Minari… - American Journal of …, 2022 - journals.physiology.org
Macrophages are one of the top players when considering immune cells involved with tissue
homeostasis. Recently, increasing evidence has demonstrated that macrophages could also …

Dual and beneficial roles of macrophages during skeletal muscle regeneration

B Chazaud, M Brigitte, H Yacoub-Youssef… - Exercise and sport …, 2009 - journals.lww.com
Macrophages are necessary for skeletal muscle regeneration after injury. Muscle recruits
inflammatory monocytes/macrophages that switch toward an anti-inflammatory profile upon …

Inflammation and skeletal muscle regeneration: leave it to the macrophages!

B Chazaud - Trends in immunology, 2020 - cell.com
Inflammation is usually considered as harmful; however, it is also necessary for tissue
recovery after injury. Macrophages exert immune and nonimmune functions throughout this …

Macrophage involvement in aging-associated skeletal muscle regeneration

CY Cui, L Ferrucci, M Gorospe - Cells, 2023 - mdpi.com
The skeletal muscle is a dynamic organ composed of contractile muscle fibers, connective
tissues, blood vessels and nerve endings. Its main function is to provide motility to the body …

Inflammation during skeletal muscle regeneration and tissue remodeling: application to exercise‐induced muscle damage management

B Chazaud - Immunology and cell biology, 2016 - Wiley Online Library
Increase in the practice of sport by more and more numerous people in the Western
countries is associated with an increase in muscle injuries, and in demand for improving …

Regulatory interactions between muscle and the immune system during muscle regeneration

JG Tidball, SA Villalta - American Journal of Physiology …, 2010 - journals.physiology.org
Recent discoveries reveal complex interactions between skeletal muscle and the immune
system that regulate muscle regeneration. In this review, we evaluate evidence that …

Macrophages are key regulators of stem cells during skeletal muscle regeneration and diseases

J Dort, P Fabre, T Molina, NA Dumont - Stem cells international, 2019 - Wiley Online Library
Muscle regeneration is a closely regulated process that involves a variety of cell types such
as satellite cells, myofibers, fibroadipogenic progenitors, endothelial cells, and inflammatory …

Macrophage plasticity and the role of inflammation in skeletal muscle repair

Y Kharraz, J Guerra, CJ Mann… - Mediators of …, 2013 - Wiley Online Library
Effective repair of damaged tissues and organs requires the coordinated action of several
cell types, including infiltrating inflammatory cells and resident cells. Recent findings have …

[HTML][HTML] Macrophages protect against muscle atrophy and promote muscle recovery in vivo and in vitro: a mechanism partly dependent on the insulin-like growth factor …

N Dumont, J Frenette - The American journal of pathology, 2010 - Elsevier
Hindlimb unloading and reloading are characterized by a major loss of muscle force and are
associated with classic leukocyte infiltration during recovery from muscle atrophy …