Introduction Acetaminophen (APAP) hepatotoxicity is the leading cause of acute liver failure
in the western world. Despite extensive investigations into the mechanisms of cell death …

Liver injury and acute liver failure caused by acetaminophen (APAP, N-acetyl-p-
aminophenol, paracetamol) overdose is a significant clinical problem in most western …

Liver injury and acute liver failure caused by an acetaminophen (APAP) overdose is a
significant clinical problem in western countries. With the introduction of the mouse model of …

Acetaminophen (APAP) overdose is the clinically most relevant drug hepatotoxicity in
western countries, and, because of translational relevance of animal models, APAP is …

Acetaminophen (N-acetyl-para-aminophenol (APAP)) is one of the most-studied drugs
worldwide. APAP causes liver toxicity after an overdose, with thousands of papers published …

Acetaminophen (APAP) is a widely used analgesic and antipyretic over-the-counter
medicine worldwide. Hepatotoxicity caused by APAP overdose is one of the leading causes …

Background The liver plays an important role in regulating the metabolic processes and is
the most frequently targeted organ by toxic chemicals. Acetaminophen (APAP) is a well …

Acetaminophen (APAP) is the most popular mild analgesic and antipyretic drug used
worldwide. APAP overdose leads to drug-induced hepatotoxicity and can cause hepatic …

Background: Drug-induced liver injury is a rare but serious clinical problem. A number of
drugs can cause severe liver injury and acute liver failure at therapeutic doses in a very …

Introduction Acetaminophen (paracetamol) is a commonly used analgesic and antipyretic
agent, which is safe in therapeutic doses. Acetaminophen poisoning due to self-harm or …