Fighting against skin aging: the way from bench to bedside

S Zhang, E Duan - Cell transplantation, 2018 - journals.sagepub.com
As the most voluminous organ of the body that is exposed to the outer environment, the skin
suffers from both intrinsic and extrinsic aging factors. Skin aging is characterized by features …

Introduction to skin aging

DJ Tobin - Journal of tissue viability, 2017 - Elsevier
Cutaneous science has seen considerable development in the last 25 years, in part due to
the Omics revolution, and the appreciation that this organ is hardwired into the body's key …

Skin aging from mechanisms to interventions: focusing on dermal aging

SH Shin, YH Lee, NK Rho, KY Park - Frontiers in Physiology, 2023 - frontiersin.org
Skin aging is a multifaceted process that involves intrinsic and extrinsic mechanisms that
lead to various structural and physiological changes in the skin. Intrinsic aging is associated …

Cell aging and cellular senescence in skin aging—Recent advances in fibroblast and keratinocyte biology

F Gruber, C Kremslehner, L Eckhart… - Experimental gerontology, 2020 - Elsevier
The aging of the skin is the most visible and obvious manifestation of organismal aging and
may serve as a predictor of life expectancy and health. It is, however, also the human desire …

Molecular mechanisms of skin aging and rejuvenation

M Kim, HJ Park - Molecular mechanisms of the aging process …, 2016 - books.google.com
The aging process in the skin is complex and influenced by more intrinsic and extrinsic
factors than any other body organ. The effects of these two types of factors overlap for the …

Skin aging: Pathophysiology and innovative therapies

F Boismal, K Serror, G Dobos, E Zuelgaray… - … Sciences: M/S, 2020 - europepmc.org
One of the major challenges of the 21 st century is the fight against aging, defined as a set of
physiological mechanisms altering the physical and intellectual capacities of human beings …

[HTML][HTML] The role of cellular senescence in skin aging and age-related skin pathologies

T Chin, Y Lee, O Dreesen - Frontiers in physiology, 2023 - frontiersin.org
Aging is the result of a gradual functional decline at the cellular, and ultimately, organismal
level, resulting in an increased risk of developing a variety of chronic illnesses, such as …

The effect of aging in primary human dermal fibroblasts

JC Lago, MB Puzzi - PloS one, 2019 - journals.plos.org
Skin aging is a complex process, and alterations in human skin due to aging have distinct
characteristic as compared to other organs. The aging of dermal cells and the biological …

Characteristics of the aging skin

MA Farage, KW Miller, P Elsner… - Advances in wound …, 2013 - liebertpub.com
Significance: Although most researches into the changes in skin with age focus on the
unwelcome aesthetic aspects of the aging skin, skin deterioration with age is more than a …

[HTML][HTML] The pathobiology of skin aging: new insights into an old dilemma

E Russell-Goldman, GF Murphy - The American journal of pathology, 2020 - Elsevier
Long considered both physiologic and inevitable, skin aging is a degenerative phenomenon
whereby both intrinsic and environmental factors conspire to produce an authentic disease …