The vertebrate annexin superfamily (AnxA) consists of 12 members of a calcium (Ca2+) and
phospholipid binding protein family which share a high structural homology. In keeping with …

Annexins are a highly conserved protein family that bind to phospholipids in a calcium (Ca
2+)–dependent manner. Studies with purified annexins, as well as overexpression and …

Annexins are a well-known multigene family of Ca2+-regulated phospholipid-binding and
membrane-binding proteins. Recent work employing annexin-knockdown or-knockout …

Despite the discovery of annexins 40 years ago, we are just beginning to understand some
of the functions of these still enigmatic proteins. Defined and characterized by their ability to …

Annexins are physiologically important proteins that play a role in calcium buffering but also
influence membrane structure, participate in Ca2+-dependent membrane repair events and …

Annexins constitute a family of Ca 2+-and phospholipid-binding proteins. Although their
functions are still not clearly defined, several members of the annexin family have been …

The annexins, are a family of calcium ion (Ca 2+)-binding proteins whose physiological
functions are poorly understood. Although many diverse functions have been proposed for …

Renal and cardiovascular disorders are very prevalent and associated with significant
morbidity and mortality. Among diverse pathogenic mechanisms, the dysregulation of …

The human genome codes for 12 annexins with highly homologous membrane‐binding
cores and unique amino termini, which endow each protein with its specific biological …

Annexins are abundant and ubiquitous proteins that bind, by their four structurally identical
domain cores, to phosphatidylserine-containing membranes in the presence of Ca 2+. Using …