Hypotension with neurovascular changes and cognitive dysfunction: An epidemiological, pathobiological, and treatment review

Y Cheng, L Lin, P Huang, J Zhang… - Chinese Medical …, 2024 - journals.lww.com
Hypotension is a leading cause of age-related cognitive impairment. The available literature
evidences that vascular factors are associated with dementia and that hypotension alters …

Hypertension, neurodegeneration, and cognitive decline

A Pacholko, C Iadecola - Hypertension, 2024 - Am Heart Assoc
Elevated blood pressure is a well-established risk factor for age-related cognitive decline.
Long linked to cognitive impairment on vascular bases, increasing evidence suggests a …

Basic Mechanisms of Brain Injury and Cognitive Decline in Hypertension

CE Baggeroer, FE Cambronero, NA Savan… - …, 2024 - Am Heart Assoc
Dementia affects almost 50 million adults worldwide, and remains a major cause of death
and disability. Hypertension is a leading risk factor for dementia, including Alzheimer …

Cerebral blood flow in Alzheimer's disease

AE Roher, JP Debbins, M Malek-Ahmadi… - Vascular health and …, 2012 - Taylor & Francis
Background Alzheimer's disease (AD) dementia is a consequence of heterogeneous and
complex interactions of age-related neurodegeneration and vascular-associated …

A study on the pathogenesis of vascular cognitive impairment and dementia: the chronic cerebral hypoperfusion hypothesis

W Yu, Y Li, J Hu, J Wu, Y Huang - Journal of clinical medicine, 2022 - mdpi.com
The pathogenic mechanisms underlying vascular cognitive impairment and dementia
(VCID) remain controversial due to the heterogeneity of vascular causes and complexity of …

Hypertension and cognitive impairment

S SHANG, Q QU - Chinese Journal of Contemporary Neurology & …, 2015 - cjcnn.org
As a leading risk factor for stroke, hypertension is also an important risk factor for cognitive
impairment. Midlife hypertension doubles the risk of dementia later in life and accelerates …

Hypertension impairs neurovascular coupling and promotes microvascular injury: role in exacerbation of Alzheimer's disease

A Csiszar, S Tarantini, GA Fülöp, T Kiss… - Geroscience, 2017 - Springer
Hypertension in the elderly substantially increases both the risk of vascular cognitive
impairment (VCI) and Alzheimer's disease (AD); however, the underlying mechanisms are …

Neurovascular and cognitive dysfunction in hypertension: epidemiology, pathobiology, and treatment

C Iadecola, RF Gottesman - Circulation research, 2019 - Am Heart Assoc
Hypertension has emerged as a leading cause of age-related cognitive impairment. Long
known to be associated with dementia caused by vascular factors, hypertension has more …

Orthostatic hypotension as a risk factor for longitudinal deterioration of cognitive function in the elderly

M Zimmermann, I Wurster, S Lerche… - European journal of …, 2020 - Wiley Online Library
Background and purpose Orthostatic hypotension is frequent with aging with a prevalence of
20%–30% in people aged 65 or older and is considered to increase the risk for coronary …

Defining the relationship between hypertension, cognitive decline, and dementia: a review

KA Walker, MC Power, RF Gottesman - Current hypertension reports, 2017 - Springer
Hypertension is a highly prevalent condition which has been established as a risk factor for
cardiovascular and cerebrovascular disease. Although the understanding of the relationship …