Cigarette smoking is a major risk factor for aortic aneurysm and dissection; however, no
causative link between smoking and these aortic disorders has been proven. In the present …

Atherosclerosis (AS) is the fundamental pathological state of many serious vascular
diseases, characterized by disorders of lipid metabolism. Ferroptosis is a type of regulated …

Smooth muscle cell (SMC) loss is the characteristic feature in the pathogenesis of aortic
dissection (AD), and ferroptosis is a novel iron-dependent regulated cell death driven by the …

Cigarette smoke is responsible for many fatal pulmonary diseases, however, the toxic
mechanism is still unclear. In this study, we first confirmed that whole cigarette smoke …

The pathogenesis of atherosclerosis is closely related to endothelial cell injury caused by
lipid peroxidation-induced ferroptosis. Tanshinone IIA (TSA) protects endothelial tissues …

Cardiovascular diseases (CVDs) are the principal cause of disease burden and death
worldwide. Ferroptosis is a new form of regulated cell death mainly characterized by altered …

A variety of programmed cell death types have been shown to participate in the loss of
smooth muscle cells (SMCs) during the development of aortic dissection (AD), but it is still …

Atherosclerosis (AS) is a major cause of cardiovascular diseases such as coronary heart
disease, heart failure and stroke. Abnormal lipid metabolism, oxidative stress and …

Ferroptosis is a form of programmed cell death caused by production of reactive oxygen
species and disequilibrium of iron homeostasis. Many chemical compounds and clinical …

Ferroptosis is a new form of regulated cell death (RCD) driven by iron-dependent lipid
peroxidation, which is morphologically and mechanistically distinct from other forms of RCD …