Single-and multifraction stereotactic radiosurgery dose/volume tolerances of the brain

MT Milano, J Grimm, A Niemierko, SG Soltys… - International Journal of …, 2021 - Elsevier
Purpose As part of the American Association of Physicists in Medicine Working Group on
Stereotactic Body Radiotherapy investigating normal tissue complication probability (NTCP) …

Irradiated volume as a predictor of brain radionecrosis after linear accelerator stereotactic radiosurgery

BJ Blonigen, RD Steinmetz, L Levin, MA Lamba… - International Journal of …, 2010 - Elsevier
PURPOSE: To investigate the correlation between volume of brain irradiated by stereotactic
radiosurgery (SRS) and the incidence of symptomatic and asymptomatic brain radionecrosis …

Single-fraction versus multifraction (3× 9 Gy) stereotactic radiosurgery for large (> 2 cm) brain metastases: a comparative analysis of local control and risk of radiation …

G Minniti, C Scaringi, S Paolini, G Lanzetta… - International Journal of …, 2016 - Elsevier
Purpose To investigate the local control and radiation-induced brain necrosis in patients
with brain metastases> 2 cm in size who received single-fraction or multifraction stereotactic …

Long-term risk of radionecrosis and imaging changes after stereotactic radiosurgery for brain metastases

ZA Kohutek, Y Yamada, TA Chan, CW Brennan… - Journal of neuro …, 2015 - Springer
Radionecrosis is a well-characterized effect of stereotactic radiosurgery (SRS) and is
occasionally associated with serious neurologic sequelae. Here, we investigated the …

Stereotactic radiosurgery for brain metastases: analysis of outcome and risk of brain radionecrosis

G Minniti, E Clarke, G Lanzetta, MF Osti, G Trasimeni… - Radiation …, 2011 - Springer
Purpose to investigate the factors affecting survival and toxicity in patients treated with
stereotactic radiosurgery (SRS), with special attention to volumes of brain receiving a …

Association between radiation necrosis and tumor biology after stereotactic radiosurgery for brain metastasis

JA Miller, EE Bennett, R Xiao, R Kotecha… - International Journal of …, 2016 - Elsevier
Background The primary dose-limiting toxicity of stereotactic radiosurgery (SRS) is radiation
necrosis (RN), which occurs after approximately 5% to 10% of treatments. This adverse …

A multi-center analysis of single-fraction versus hypofractionated stereotactic radiosurgery for the treatment of brain metastasis

JS Remick, E Kowalski, R Khairnar, K Sun, E Morse… - Radiation …, 2020 - Springer
Abstract Background Hypofractionated-SRS (HF-SRS) may allow for improved local control
and a reduced risk of radiation necrosis compared to single-fraction-SRS (SF-SRS) …

Single versus multifraction stereotactic radiosurgery for large brain metastases: an international meta-analysis of 24 trials

EJ Lehrer, JL Peterson, NG Zaorsky, PD Brown… - International Journal of …, 2019 - Elsevier
Purpose Multifraction (MF) stereotactic radiosurgery (SRS) purportedly reduces
radionecrosis risk over single-fraction (SF) SRS in the treatment of large brain metastases …

Tumor control probability of radiosurgery and fractionated stereotactic radiosurgery for brain metastases

KJ Redmond, C Gui, S Benedict, MT Milano… - International Journal of …, 2021 - Elsevier
Purpose As part of the American Association of Physicists in Medicine Working Group on
Stereotactic Body Radiotherapy, tumor control probability (TCP) after stereotactic …

Adverse radiation effect after stereotactic radiosurgery for brain metastases: incidence, time course, and risk factors

PK Sneed, J Mendez, JGM Vemer-van den Hoek… - Journal of …, 2015 - thejns.org
OBJECT The authors sought to determine the incidence, time course, and risk factors for
overall adverse radiation effect (ARE) and symptomatic ARE after stereotactic radiosurgery …