[HTML][HTML] How efficient are alendronate-nano/biomaterial combinations for anti-osteoporosis therapy? An evidence-based review of the literature
J Klara, J Lewandowska-Łańcucka - International journal of …, 2022 - ncbi.nlm.nih.gov
Osteoporosis is defined as a systemic skeletal disease characterized by low bone mass and
microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility …
microarchitectural deterioration of bone tissue, with a consequent increase in bone fragility …
[HTML][HTML] Nano-based biomaterials as drug delivery systems against osteoporosis: a systematic review of preclinical and clinical evidence
F Salamanna, A Gambardella, D Contartese, A Visani… - Nanomaterials, 2021 - mdpi.com
Osteoporosis (OP) is one of the most significant causes of morbidity, particularly in post-
menopausal women and older men. Despite its remarkable occurrence, the search for an …
menopausal women and older men. Despite its remarkable occurrence, the search for an …
Emerging nano-scale delivery systems for the treatment of osteoporosis
AP Dayanandan, WJ Cho, H Kang, AB Bello… - Biomaterials …, 2023 - spj.science.org
Osteoporosis is a pathological condition characterized by an accelerated bone resorption
rate, resulting in decreased bone density and increased susceptibility to fractures …
rate, resulting in decreased bone density and increased susceptibility to fractures …
[HTML][HTML] Bone diseases: Current approach and future perspectives in drug delivery systems for bone targeted therapeutics
G Chindamo, S Sapino, E Peira, D Chirio… - Nanomaterials, 2020 - mdpi.com
Bone diseases include a wide group of skeletal-related disorders that cause mobility
limitations and mortality. In some cases, eg, in osteosarcoma (OS) and metastatic bone …
limitations and mortality. In some cases, eg, in osteosarcoma (OS) and metastatic bone …
Nanotechnology for targeted drug delivery to treat osteoporosis
Bone diseases such as rheumatoid arthritis, Paget's disease, and osteoporosis cause
mortality and mobility limits. Nanomedicine and nano delivery systems have been utilised to …
mortality and mobility limits. Nanomedicine and nano delivery systems have been utilised to …
Dual targeting anti-osteoporotic therapy through potential nanotherapeutic approaches
Osteoporosis is characterised by a major public health burden, particularly taking into
account the ageing global population. Therapeutic modalities for osteoporosis are …
account the ageing global population. Therapeutic modalities for osteoporosis are …
In vitro/ex vivo evaluation of multifunctional collagen/chitosan/hyaluronic acid hydrogel-based alendronate delivery systems
J Klara, A Hinz, M Bzowska, W Horak… - International Journal of …, 2024 - Elsevier
Injectable hydrogel-based materials have emerged as promising alendronate (ALN) delivery
systems for the treatment of osteoporosis. However, their intrinsic permeability limits the …
systems for the treatment of osteoporosis. However, their intrinsic permeability limits the …
Alendronate-decorated nanoparticles as bone-targeted alendronate carriers for potential osteoporosis treatment
C Jing, B Li, H Tan, C Zhang, H Liang… - ACS Applied Bio …, 2021 - ACS Publications
Osteoporosis is a skeletal disorder characterized by a low bone mass and density.
Alendronate (Alen), a second-generation bisphosphonate drug, was indicated as the first …
Alendronate (Alen), a second-generation bisphosphonate drug, was indicated as the first …
[HTML][HTML] Towards controlling the local bone tissue remodeling—multifunctional injectable composites for osteoporosis treatment
J Klara, S Onak, A Kowalczyk, W Horak… - International Journal of …, 2023 - mdpi.com
Alendronate (ALN) is the most commonly prescribed oral nitrogen-containing
bisphosphonate for osteoporosis therapy. However, its administration is associated with …
bisphosphonate for osteoporosis therapy. However, its administration is associated with …
Enteric-coated alendronate sodium nanoliposomes: a novel formula to overcome barriers for the treatment of osteoporosis
KM Hosny, OAA Ahmed… - Expert opinion on drug …, 2013 - Taylor & Francis
Background and objectives: Alendronate sodium (ALS) is the most common drug used for
the treatment of osteoporosis. The challenges facing ALS use include: very poor oral …
the treatment of osteoporosis. The challenges facing ALS use include: very poor oral …