Background Consumption of high-fat diet (HF) leads to hyperphagia and increased body
weight in male rodents. Female rodents are relatively resistant to hyperphagia and weight …

Objective Ad libitum high‐fat diets (HFDs) spontaneously increase caloric intake in rodents,
which correlates positively with weight gain. However, it remains unclear why rodents …

We show that chronic high fat diet (HFD) feeding affects the hypothalamus of male but not
female mice. In our study we demonstrate that palmitic acid and sphingolipids accumulate in …

Abstract Background/Objective Female mice are often excluded from diet-induced obesity
studies as they are more resistant to the obesifying effects of a high-fat diet (HFD). However …

Prevalence and health consequences of obesity differ between men and women. Yet, most
preclinical studies investigating the etiology of obesity have, to date, been conducted in …

While most rats gain weight when placed on a high-fat diet (HFD), some strains resist HFD-
induced weight gain. To maintain weight, obesity-resistant (OR) rats must either eat less …

High-fat diet (HFD) induced obesity is associated not only with metabolic dysregulation, eg,
impaired glucose homeostasis and insulin sensitivity, but also with neurological dysfunction …

Aims The present study aims to compare the responses between male and female C57BL/6
mice to multiple metabolic challenges to understand the importance of sex in the control of …

Time-restricted feeding ameliorates the deleterious effects of a high-fat diet on body weight
and metabolism in young adult mice. Because obesity is highly prevalent in the middle-aged …

Objective To investigate the variations in body weight, food intake, and body composition of
both male and female C57BL/6J mice during a diet‐induced obesity model with high‐fat diet …