[HTML][HTML] Single-cell analysis reveals landscape of endometrial cancer response to estrogen and identification of early diagnostic markers
C Dong, L Zhao, X Liu, L Dang, X Zhang - Plos one, 2024 - journals.plos.org
Background The development of endometrial cancer (EC) is closely related to the abnormal
activation of the estrogen signaling pathway. Effective diagnostic markers are important for …
activation of the estrogen signaling pathway. Effective diagnostic markers are important for …
[HTML][HTML] Comprehensive analysis and experimental validation of a novel Estrogen/Progesterone-related prognostic signature for endometrial cancer
J Yu, HW Yao, TT Liu, D Wang, JH Shi… - Journal of Personalized …, 2022 - mdpi.com
Estrogen and progesterone are the major determinants of the occurrence and development
of endometrial cancer (EC), which is one of the most common gynecological cancers …
of endometrial cancer (EC), which is one of the most common gynecological cancers …
[HTML][HTML] Single-cell transcriptomic analysis highlights origin and pathological process of human endometrioid endometrial carcinoma
X Ren, J Liang, Y Zhang, N Jiang, Y Xu, M Qiu… - Nature …, 2022 - nature.com
Endometrial cancers are complex ecosystems composed of cells with distinct phenotypes,
genotypes, and epigenetic states. Current models do not adequately reflect oncogenic origin …
genotypes, and epigenetic states. Current models do not adequately reflect oncogenic origin …
[HTML][HTML] Integration of genomic and clinical retrospective data to predict endometrioid endometrial cancer recurrence
J Gonzalez-Bosquet, S Gabrilovich… - International journal of …, 2022 - mdpi.com
Endometrial cancer (EC) incidence and mortality continues to rise. Molecular profiling of EC
promises improvement of risk assessment and treatment selection. However, we still lack …
promises improvement of risk assessment and treatment selection. However, we still lack …
Integrative Analysis of Multi-Omic Data for the Characteristics of Endometrial Cancer
T Li, Z Ruan, C Song, F Yin, T Zhang, L Shi, M Zuo… - ACS …, 2024 - ACS Publications
Endometrial cancer (EC) is a frequently diagnosed gynecologic cancer. Identifying reliable
prognostic genes for predicting EC onset is crucial for reducing patient morbidity and …
prognostic genes for predicting EC onset is crucial for reducing patient morbidity and …
[HTML][HTML] Integrated transcriptome and multiple activated pathways in endometrial cancer
Q Jin, X Jiang, X Du, W Hu, S Bai, X Wang, B Xu… - Frontiers in …, 2021 - frontiersin.org
Because the incidence of endometrial cancer is notably increasing worldwide, it has
become the leading gynecologic cancer in the United States. Standard treatment results in …
become the leading gynecologic cancer in the United States. Standard treatment results in …
[HTML][HTML] Increased epithelial stem cell traits in advanced endometrial endometrioid carcinoma
SJ Chang, TY Wang, CY Tsai, TF Hu, MDT Chang… - BMC genomics, 2009 - Springer
Background It has been recognized cancer cells acquire characters reminiscent of those of
normal stem cells, and the degree of stem cell gene expression correlates with patient …
normal stem cells, and the degree of stem cell gene expression correlates with patient …
[HTML][HTML] Exploring the role of macrophages in the progression from atypical hyperplasia to endometrial carcinoma through single-cell transcriptomics and bulk …
X Song, R Na, N Peng, W Cao, Y Ke - Frontiers in endocrinology, 2023 - frontiersin.org
Introduction In this study, we aimed to identify key genes in endometrial cancer by
conducting single-cell analysis of macrophages. Methods We sourced clinical data from the …
conducting single-cell analysis of macrophages. Methods We sourced clinical data from the …
[HTML][HTML] Meta-analysis of gene expression studies in endometrial cancer identifies gene expression profiles associated with aggressive disease and patient outcome
Although endometrioid endometrial cancer (EEC; comprising~ 80% of all endometrial
cancers diagnosed) is typically associated with favourable patient outcome, a significant …
cancers diagnosed) is typically associated with favourable patient outcome, a significant …
Integrated multi-omic analyses reveals clinical relevance of endometrial cancer cell line models
J Loffredo, D Tommarello, T Abulez, W Ao, P Teng… - Gynecologic …, 2021 - Elsevier
Objectives: Endometrial cancer (EC) cell lines models established from diverse ancestral
backgrounds and reflective of in situ disease characteristics are necessary to support …
backgrounds and reflective of in situ disease characteristics are necessary to support …
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